PDB entry 2bz6

View 2bz6 on RCSB PDB site
Description: orally available factor7a inhibitor
Class: hydrolase
Keywords: serine protease, coagulation, enzyme complex, hydrolase
Deposited on 2005-08-11, released 2006-02-22
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-31.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: 0.168
AEROSPACI score: 0.61 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'H':
    Compound: blood coagulation factor viia
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2bz6h_
  • Chain 'L':
    Compound: blood coagulation factor viia
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2bz6l_
  • Heterogens: 346, SO4, CA, HOH

PDB Chain Sequences:

  • Chain 'H':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2bz6H (H:)
ivggkvcpkgecpwqvlllvngaqlcggtlintiwvvsaahcfdkiknwrnliavlgehd
lsehdgdeqsrrvaqviipstyvpgttnhdiallrlhqpvvltdhvvplclpertfsert
lafvrfslvsgwgqlldrgatalelmvlnvprlmtqdclqqsrkvgdspniteymfcagy
sdgskdsckgdsggphathyrgtwyltgivswgqgcatvghfgvytrvsqyiewlqklmr
seprpgvllrapfp

  • Chain 'L':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2bz6L (L:)
icvnenggceqycsdhtgtkrscrchegyslladgvsctptveypcgkipile