PDB entry 2bwg

View 2bwg on RCSB PDB site
Description: Structure of human guanosine monophosphate reductase GMPR1 in complex with GMP
Class: oxidoreductase
Keywords: nucleotide pathway, tim barrel, oxidoreductase
Deposited on 2005-07-13, released 2005-07-20
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-10-23, with a file datestamp of 2019-10-18.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: N/A
AEROSPACI score: 0.22 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: gmp reductase I
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P36959
      • variant (277)
    Domains in SCOPe 2.08: d2bwga_
  • Chain 'B':
    Compound: gmp reductase I
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P36959
      • variant (277)
    Domains in SCOPe 2.08: d2bwgb_
  • Chain 'C':
    Compound: gmp reductase I
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P36959
      • variant (277)
    Domains in SCOPe 2.08: d2bwgc_
  • Chain 'D':
    Compound: gmp reductase I
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P36959
      • variant (277)
    Domains in SCOPe 2.08: d2bwgd_
  • Heterogens: K, 5GP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2bwgA (A:)
mhhhhhhssgvdlgtenlyfqsmpridadlkldfkdvllrpkrsslksraevdlertftf
rnskqtysgipiivanmdtvgtfemaavmsqhsmftaihkhyslddwklfatnhpeclqn
vavssgsgqndlekmtsileavpqvkficldvangysehfvefvklvrakfpehtimagn
vvtgemveelilsgadiikvgvgpgsvcttrtktgvgypqlsaviecadsahglkghiis
dggctcpgdvakafgagadfvmlggmfsghtecagevierngrklklfygmssdtamnkh
aggvaeyrasegktvevpykgdventildilgglrstctyvgaaklkelsrratfirvtq
qhntvfs

    Sequence, based on observed residues (ATOM records): (download) 
    >2bwgA (A:)
pridadlkldfkdvllrpkrsslksraevdlertftfrnskqtysgipiivanmdtvgtf
emaavmsqhsmftaihkhyslddwklfatnhpeclqnvavssgsgqndlekmtsileavp
qvkficldvangysehfvefvklvrakfpehtimagnvvtgemveelilsgadiikvgvg
pgsvcttrtktgvgypqlsaviecadsahglkghiisdggctcpgdvakafgagadfvml
ggmfsghtecagevierngrklklfygmssdtamnkhgvaeyrasegktvevpykgdven
tildilgglrstctyvgaaklkelsrratfirvtq

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2bwgB (B:)
mhhhhhhssgvdlgtenlyfqsmpridadlkldfkdvllrpkrsslksraevdlertftf
rnskqtysgipiivanmdtvgtfemaavmsqhsmftaihkhyslddwklfatnhpeclqn
vavssgsgqndlekmtsileavpqvkficldvangysehfvefvklvrakfpehtimagn
vvtgemveelilsgadiikvgvgpgsvcttrtktgvgypqlsaviecadsahglkghiis
dggctcpgdvakafgagadfvmlggmfsghtecagevierngrklklfygmssdtamnkh
aggvaeyrasegktvevpykgdventildilgglrstctyvgaaklkelsrratfirvtq
qhntvfs

    Sequence, based on observed residues (ATOM records): (download) 
    >2bwgB (B:)
pridadlkldfkdvllrpkrsslksraevdlertftfrnskqtysgipiivanmdtvgtf
emaavmsqhsmftaihkhyslddwklfatnhpeclqnvavssgsgqndlekmtsileavp
qvkficldvangysehfvefvklvrakfpehtimagnvvtgemveelilsgadiikvgvg
pgsvcttrtktgvgypqlsaviecadsahglkghiisdggctcpgdvakafgagadfvml
ggmfsghtecagevirklklfygmssdtamnkhvaeyrasegktvevpykgdventildi
lgglrstctyvgaaklkelsrratfirvt

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2bwgC (C:)
mhhhhhhssgvdlgtenlyfqsmpridadlkldfkdvllrpkrsslksraevdlertftf
rnskqtysgipiivanmdtvgtfemaavmsqhsmftaihkhyslddwklfatnhpeclqn
vavssgsgqndlekmtsileavpqvkficldvangysehfvefvklvrakfpehtimagn
vvtgemveelilsgadiikvgvgpgsvcttrtktgvgypqlsaviecadsahglkghiis
dggctcpgdvakafgagadfvmlggmfsghtecagevierngrklklfygmssdtamnkh
aggvaeyrasegktvevpykgdventildilgglrstctyvgaaklkelsrratfirvtq
qhntvfs

    Sequence, based on observed residues (ATOM records): (download) 
    >2bwgC (C:)
pridadlkldfkdvllrpkrsslksraevdlertftfrnskqtysgipiivanmdtvgtf
emaavmsqhsmftaihkhyslddwklfatnhpeclqnvavssgsgqndlekmtsileavp
qvkficldvangysehfvefvklvrakfpehtimagnvvtgemveelilsgadiikvgvg
pgsvcttrtktgvgypqlsaviecadsahglkghiisdggctcpgdvakafgagadfvml
ggmfsghtecagevirklklfygmssdtamnkhvaeyrasegktvevpykgdventildi
lgglrstctyvgaaklkelsrratfirvt

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2bwgD (D:)
mhhhhhhssgvdlgtenlyfqsmpridadlkldfkdvllrpkrsslksraevdlertftf
rnskqtysgipiivanmdtvgtfemaavmsqhsmftaihkhyslddwklfatnhpeclqn
vavssgsgqndlekmtsileavpqvkficldvangysehfvefvklvrakfpehtimagn
vvtgemveelilsgadiikvgvgpgsvcttrtktgvgypqlsaviecadsahglkghiis
dggctcpgdvakafgagadfvmlggmfsghtecagevierngrklklfygmssdtamnkh
aggvaeyrasegktvevpykgdventildilgglrstctyvgaaklkelsrratfirvtq
qhntvfs

    Sequence, based on observed residues (ATOM records): (download) 
    >2bwgD (D:)
pridadlkldfkdvllrpkrsslksraevdlertftfrnskqtysgipiivanmdtvgtf
emaavmsqhsmftaihkhyslddwklfatnhpeclqnvavssgsgqndlekmtsileavp
qvkficldvangysehfvefvklvrakfpehtimagnvvtgemveelilsgadiikvgvg
pgsvcttrtktgvgypqlsaviecadsahglkghiisdggctcpgdvakafgagadfvml
ggmfsghtecagevirklklfygmssdtamnkhaeyrasegktvevpykgdventildil
gglrstctyvgaaklkelsrratfirvt