PDB entry 2bu8

View 2bu8 on RCSB PDB site
Description: crystal structures of human pyruvate dehydrogenase kinase 2 containing physiological and synthetic ligands
Class: transferase
Keywords: transferase, pyruvate dehydrogenase kinase 2 ghkl motif regulation
Deposited on 2005-06-08, released 2006-02-02
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-05-15, with a file datestamp of 2019-05-10.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: N/A
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: pyruvate dehydrogenase kinase isoenzyme 2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2BU8 (0-1)
    • Uniprot Q15119 (2-End)
    Domains in SCOPe 2.08: d2bu8a1, d2bu8a2
  • Heterogens: ADP, MG, TF4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2bu8A (A:)
gsapkyiehfskfspsplsmkqfldfgssnacektsftflrqelpvrlanimkeinllpd
rvlstpsvqlvqswyvqslldimefldkdpedhrtlsqftdalvtirnrhndvvptmaqg
vleykdtygddpvsnqniqyfldrfylsrisirmlinqhtlifdgstnpahpkhigsidp
ncnvsevvkdaydmakllcdkyymaspdleiqeinaanskqpihmvyvpshlyhmlfelf
knamratveshesslilppikvmvalgeedlsikmsdrgggvplrkierlfsymystapt
pqpgtggtplagfgyglpisrlyakyfqgdlqlfsmegfgtdaviylkalstdsverlpv
ynksawrhyqtiqeagdwcvpstepkntstyrvs

    Sequence, based on observed residues (ATOM records): (download) 
    >2bu8A (A:)
gsapkyiehfskfspsplsmkqfldfgssnacektsftflrqelpvrlanimkeinllpd
rvlstpsvqlvqswyvqslldimefldkdpedhrtlsqftdalvtirnrhndvvptmaqg
vleykdtygddpvsnqniqyfldrfylsrisirmlinqhtlifdgstnpahpkhigsidp
ncnvsevvkdaydmakllcdkyymaspdleiqeinaanskqpihmvyvpshlyhmlfelf
knamratveshesslilppikvmvalgeedlsikmsdrgggvplrkierlfsymystpla
gfgyglpisrlyakyfqgdlqlfsmegfgtdaviylkalstdsverlpvynksawrhyqt