PDB entry 2bu5

View 2bu5 on RCSB PDB site
Description: crystal structures of human pyruvate dehydrogenase kinase 2 containing physiological and synthetic ligands
Class: transferase
Keywords: transferase, pyruvate dehydrogenase kinase 2, ghkl motif regulation
Deposited on 2005-06-08, released 2006-02-02
The last revision prior to the SCOPe 2.05 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.35 Å
R-factor: 0.2371
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: pyruvate dehydrogenase kinase isoenzyme 2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2BU5 (0-1)
    • Uniprot Q15119 (2-End)
    Domains in SCOPe 2.05: d2bu5a1, d2bu5a2
  • Heterogens: TF1, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2bu5A (A:)
gsapkyiehfskfspsplsmkqfldfgssnacektsftflrqelpvrlanimkeinllpd
rvlstpsvqlvqswyvqslldimefldkdpedhrtlsqftdalvtirnrhndvvptmaqg
vleykdtygddpvsnqniqyfldrfylsrisirmlinqhtlifdgstnpahpkhigsidp
ncnvsevvkdaydmakllcdkyymaspdleiqeinaanskqpihmvyvpshlyhmlfelf
knamratveshesslilppikvmvalgeedlsikmsdrgggvplrkierlfsymystapt
pqpgtggtplagfgyglpisrlyakyfqgdlqlfsmegfgtdaviylkalstdsverlpv
ynksawrhyqtiqeagdwcvpstepkntstyrvs

    Sequence, based on observed residues (ATOM records): (download) 
    >2bu5A (A:)
gsapkyiehfskfspsplsmkqfldfsnacektsftflrqelpvrlanimkeinllpdrv
lstpsvqlvqswyvqslldimefldkdpedhrtlsqftdalvtirnrhndvvptmaqgvl
eykdtygddpvsnqniqyfldrfylsrisirmlinqhtlifdkhigsidpncnvsevvkd
aydmakllcdkyymaspdleiqeinaanskqpihmvyvpshlyhmlfelfknamratves
hesslilppikvmvalgeedlsikmsdrgggvplrkierlfsymystapgyglpisrlya
kyfqgdlqlfsmegfgtdaviylkalstdsverlpvynksawrhyqtiqeagdwcv