PDB entry 2btz

View 2btz on RCSB PDB site
Description: crystal structures of human pyruvate dehydrogenase kinase 2 containing physiological and synthetic ligands
Class: transferase
Keywords: ghkl motif regulation, transferase
Deposited on 2005-06-08, released 2006-02-02
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.2658
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: pyruvate dehydrogenase kinase isoenzyme 2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2BTZ (0-1)
    • Uniprot Q15119 (2-End)
    Domains in SCOPe 2.06: d2btza1, d2btza2

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2btzA (A:)
gsapkyiehfskfspsplsmkqfldfgssnacektsftflrqelpvrlanimkeinllpd
rvlstpsvqlvqswyvqslldimefldkdpedhrtlsqftdalvtirnrhndvvptmaqg
vleykdtygddpvsnqniqyfldrfylsrisirmlinqhtlifdgstnpahpkhigsidp
ncnvsevvkdaydmakllcdkyymaspdleiqeinaanskqpihmvyvpshlyhmlfelf
knamratveshesslilppikvmvalgeedlsikmsdrgggvplrkierlfsymystapt
pqpgtggtplagfgyglpisrlyakyfqgdlqlfsmegfgtdaviylkalstdsverlpv
ynksawrhyqtiqeagdwcvpstepkntstyrvs

    Sequence, based on observed residues (ATOM records): (download) 
    >2btzA (A:)
gsapkyiehfskfspsplsmkqfldfgssnacektsftflrqelpvrlanimkeinllpd
rvlstpsvqlvqswyvqslldimefldkdpedhrtlsqftdalvtirnrhndvvptmaqg
vleykdtygddpvsnqniqyfldrfylsrisirmlinqhtlifdkhigsidpncnvsevv
kdaydmakllcdkyymaspdleiqeinaanskqpihmvyvpshlyhmlfelfknamratv
eshesslilppikvmvalgeedlsikmsdrgggvplrkierlfsymystapgyglpisrl
yakyfqgdlqlfsmegfgtdaviylkalstdsverlpvynksawrhyqtiqeagdwcv