PDB entry 2bre

View 2bre on RCSB PDB site
Description: structure of a hsp90 inhibitor bound to the n-terminus of yeast hsp90.
Class: chaperone
Keywords: chaperone-complex, ATP-binding, chaperone, heat shock, inhibitor, multigene family
Deposited on 2005-05-04, released 2005-09-29
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-02-28, with a file datestamp of 2018-02-23.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: ATP-dependent molecular chaperone hsp82
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2brea_
  • Chain 'B':
    Compound: ATP-dependent molecular chaperone hsp82
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2breb_
  • Heterogens: KJ2, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2breA (A:)
    masetfefqaeitqlmsliintvysnkeiflrelisnasdaldkirykslsdpkqletep
    dlfiritpkpeqkvleirdsgigmtkaelinnlgtiaksgtkafmealsagadvsmigqf
    gvgfyslflvadrvqvisksnddeqyiwesnaggsftvtldevnerigrgtilrlflkdd
    qleyleekrikevikrhsefvaypiqlvvtkevekevpi
    

    Sequence, based on observed residues (ATOM records): (download)
    >2breA (A:)
    asetfefqaeitqlmsliintvysnkeiflrelisnasdaldkirykslsdpkqletepd
    lfiritpkpeqkvleirdsgigmtkaelinnlgtiaksgtkafmealsagadvsmigqfg
    vgfyslflvadrvqvisksnddeqyiwesnaggsftvtldevnerigrgtilrlflkddq
    leyleekrikevikrhsefvaypiqlvvtkeve
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >2breB (B:)
    masetfefqaeitqlmsliintvysnkeiflrelisnasdaldkirykslsdpkqletep
    dlfiritpkpeqkvleirdsgigmtkaelinnlgtiaksgtkafmealsagadvsmigqf
    gvgfyslflvadrvqvisksnddeqyiwesnaggsftvtldevnerigrgtilrlflkdd
    qleyleekrikevikrhsefvaypiqlvvtkevekevpi
    

    Sequence, based on observed residues (ATOM records): (download)
    >2breB (B:)
    asetfefqaeitqlmsliintvysnkeiflrelisnasdaldkirykslsdpkqletepd
    lfiritpkpeqkvleirdsgigmtkaelinnlgtiaksgtkafmealsagadvsmigqfg
    vgfyslflvadrvqvisksnddeqyiwesnaggsftvtldevnerigrgtilrlflkddq
    leyleekrikevikrhsefvaypiqlvvtkevekevpi