PDB entry 2boh

View 2boh on RCSB PDB site
Description: crystal structure of factor xa in complex with compound "1"
Class: complex (hydrolase/inhibitor)
Keywords: protein-inhibitor complex, blood coagulation factor, serine proteinase, rational drug design, calcium-binding, egf-like domain, gamma-carboxyglutamic acid, glycoprotein, hydrolase, hydroxylation, plasma, polymorphism, protease, repeat, serine protease, vitamin k, zymogen, hydrolase-inhibitor complex
Deposited on 2005-04-11, released 2006-04-05
The last revision prior to the SCOP 1.73 freeze date was dated 2006-04-05, with a file datestamp of 2007-06-28.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.207
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: coagulation factor xa
    Species: HOMO SAPIENS
    Gene:
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d2boha1
  • Chain 'B':
    Compound: coagulation factor xa
    Species: HOMO SAPIENS
    Gene:
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d2bohb1
  • Heterogens: CA, IIA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2bohA (A:)
    eemkkghlerecmeetcsyeearevfedsdktnefwnkykdgdqcetspcqnqgkckdgl
    geytctclegfegkncelftrklcsldngdcdqfcheeqnsvvcscargytladngkaci
    ptgpypcgkqtler
    

    Sequence, based on observed residues (ATOM records): (download)
    >2bohA (A:)
    rklcsldngdcdqfcheeqnsvvcscargytladngkaciptgpypcgkqtler
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >2bohB (B:)
    ivggqeckdgecpwqallineenegfcggtilsefyiltaahclyqakrfkvrvgdrnte
    qeeggeavhevevvikhnrftketydfdiavlrlktpitfrmnvapaclperdwaestlm
    tqktgivsgfgrthekgrqstrlkmlevpyvdrnscklsssfiitqnmfcagydtkqeda
    cqgdsggphvtrfkdtyfvtgivswgegcarkgkygiytkvtaflkwidrsmktrglpka
    kshapevitssplk
    

    Sequence, based on observed residues (ATOM records): (download)
    >2bohB (B:)
    ivggqeckdgecpwqallineenegfcggtilsefyiltaahclyqakrfkvrvgdrnte
    qeeggeavhevevvikhnrftketydfdiavlrlktpitfrmnvapaclperdwaestlm
    tqktgivsgfgrthekgrqstrlkmlevpyvdrnscklsssfiitqnmfcagydtkqeda
    cqgdsggphvtrfkdtyfvtgivswgegcarkgkygiytkvtaflkwidrsmktr