PDB entry 2bnq

View 2bnq on RCSB PDB site
Description: structural and kinetic basis for heightened immunogenicity of t cell vaccines
Class: immune system/receptor
Keywords: immune system/receptor, immune system/receptor/complex, tcr, MHC, immunodominance, flu, complex, peptide, transmembrane, glycoprotein, signal, polymorphism, T-cell, receptor, superagonist peptide T-cell vaccines
Deposited on 2005-03-31, released 2005-05-23
The last revision prior to the SCOPe 2.03 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: 0.226
AEROSPACI score: 0.51 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: hla class I histocompatibility antigen
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d2bnqa1, d2bnqa2
  • Chain 'B':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2BNQ (2-End)
    • Uniprot P61769 (1-99)
    Domains in SCOPe 2.03: d2bnqb_
  • Chain 'C':
    Compound: synthetic peptide
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
  • Chain 'D':
    Compound: T-cell receptor alpha chain v region
    Species: Homo sapiens [TaxId:9606]
    Domains in SCOPe 2.03: d2bnqd1, d2bnqd2
  • Chain 'E':
    Compound: T-cell receptor beta chain c region
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d2bnqe1, d2bnqe2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >2bnqA (A:)
    gshsmryfftsvsrpgrgeprfiavgyvddtqfvrfdsdaasqrmeprapwieqegpeyw
    dgetrkvkahsqthrvdlgtlrgyynqseagshtvqrmygcdvgsdwrflrgyhqyaydg
    kdyialkedlrswtaadmaaqttkhkweaahvaeqlraylegtcvewlrrylengketlq
    rtdapkthmthhavsdheatlrcwalsfypaeitltwqrdgedqtqdtelvetrpagdgt
    fqkwaavvvpsgqeqrytchvqheglpkpltlrwep
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >2bnqB (B:)
    miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
    wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
    

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download)
    >2bnqD (D:)
    qevtqipaalsvpegenlvlncsftdsaiynlqwfrqdpgkgltsllliqssqreqtsgr
    lnasldkssgrstlyiaasqpgdsatylcavrptsggsyiptfgrgtslivhpyiqnpdp
    avyqlrdskssdksvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsavawsn
    ksdfacanafnnsiipedtffps
    

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records: (download)
    >2bnqE (E:)
    gvtqtpkfqvlktgqsmtlqcaqdmnheymswyrqdpgmglrlihysvgagitdqgevpn
    gynvsrsttedfplrllsaapsqtsvyfcassyvgntgelffgegsrltvledlknvfpp
    evavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqplkeqpal
    ndsryalssrlrvsatfwqdprnhfrcqvqfyglsendewtqdrakpvtqivsaeawgra
    d