PDB entry 2bhk

View 2bhk on RCSB PDB site
Description: crystal structure of human growth and differentiation factor 5 (gdf5)
Class: growth factor
Keywords: growth factor, growth differentiation factor, bone morphogenetic factor, hormone-receptor interaction, cystine knot, preformed receptor dimer, cytokine, dwarfism, glycoprotein
Deposited on 2005-01-12, released 2005-03-11
The last revision prior to the SCOPe 2.01 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.168
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: growth differentiation factor 5
  Species: Homo sapiens [TaxId:9606]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P43026 (Start-119)
  Domains in SCOPe 2.01: d2bhka_
• Heterogens: IPA, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence, based on SEQRES records: (download)
  

  >2bhkA (A:)
  aplatrqgkrpsknlkarcsrkalhvnfkdmgwddwiiapleyeafhceglcefplrshl
  eptnhaviqtlmnsmdpestpptccvptrlspisilfidsannvvykqyedmvvescgcr
  

  
  Sequence, based on observed residues (ATOM records): (download)
  

  >2bhkA (A:)
  karcsrkalhvnfkdmgwddwiiapleyeafhceglcefplrshleptnhaviqtlmnsm
  dpestpptccvptrlspisilfidsannvvykqyedmvvescgcr