PDB entry 2bg6

View 2bg6 on RCSB PDB site
Description: Bacillus cereus metallo-beta-lactamase (BcII) Arg (121) Cys mutant. Solved at pH5 using 20 Micromolar ZnSO4 in the buffer. 1mM DTT was used as a reducing agent. Cys221 is oxidized.
Class: hydrolase
Keywords: hydrolase, zinc, metallo-beta-lactamase, antibiotic resistance
Deposited on 2004-12-17, released 2005-03-31
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-05-22, with a file datestamp of 2019-05-17.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: N/A
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: beta-lactamase II
    Species: Bacillus cereus [TaxId:1396]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P04190 (212-226)
      • engineered mutation (90)
    Domains in SCOPe 2.08: d2bg6a_
  • Chain 'B':
    Compound: beta-lactamase II
    Species: Bacillus cereus [TaxId:1396]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P04190 (212-226)
      • engineered mutation (90)
    Domains in SCOPe 2.08: d2bg6b_
  • Heterogens: GOL, ZN, SO4, AZI, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2bg6A (A:)
sqkvektviknetgtisisqlnknvwvhtelgsfngeavpsnglvlntskglvlvdsswd
dkltkeliemvekkfqkrvtdviithahadciggiktlkergikahstaltaelakkngy
eeplgdlqtvtnlkfgnmkvetfypgkghtednivvwlpqynilvggclvkstsakdlgn
vadayvnewstsienvlkryrninavvpghgevgdkglllhtldllk

    Sequence, based on observed residues (ATOM records): (download) 
    >2bg6A (A:)
tviknetgtisisqlnknvwvhtelgavpsnglvlntskglvlvdsswddkltkeliemv
ekkfqkrvtdviithahadciggiktlkergikahstaltaelakkngyeeplgdlqtvt
nlkfgnmkvetfypgkghtednivvwlpqynilvggclvkstsakdlgnvadayvnewst
sienvlkryrninavvpghgevgdkglllhtldllk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2bg6B (B:)
sqkvektviknetgtisisqlnknvwvhtelgsfngeavpsnglvlntskglvlvdsswd
dkltkeliemvekkfqkrvtdviithahadciggiktlkergikahstaltaelakkngy
eeplgdlqtvtnlkfgnmkvetfypgkghtednivvwlpqynilvggclvkstsakdlgn
vadayvnewstsienvlkryrninavvpghgevgdkglllhtldllk

    Sequence, based on observed residues (ATOM records): (download) 
    >2bg6B (B:)
ktviknetgtisisqlnknvwvhtelgsavpsnglvlntskglvlvdsswddkltkelie
mvekkfqkrvtdviithahadciggiktlkergikahstaltaelakkngyeeplgdlqt
vtnlkfgnmkvetfypgkghtednivvwlpqynilvggclvkstsakdlgnvadayvnew
stsienvlkryrninavvpghgevgdkglllhtldllk