PDB entry 2beh

View 2beh on RCSB PDB site
Description: Crystal structure of antithrombin variant S137A/V317C/T401C with plasma latent antithrombin
Class: blood clotting
Keywords: antithrombin dimer, BLOOD CLOTTING
Deposited on 2005-10-24, released 2005-11-01
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-25.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: 0.219
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'I':
    Compound: antithrombin-III
    Species: Homo sapiens [TaxId:9606]
    Gene: SERPINC1, AT3
    Database cross-references and differences (RAF-indexed):
    • Uniprot P01008
      • engineered (136)
      • engineered (316)
      • engineered (400)
    Domains in SCOPe 2.07: d2behi_
  • Chain 'L':
    Compound: antithrombin-III
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2behl_
  • Heterogens: NAG, GOL, HOH

PDB Chain Sequences:

  • Chain 'I':
    Sequence, based on SEQRES records: (download)
    >2behI (I:)
    hgspvdictakprdipmnpmciyrspekkatedegseqkipeatnrrvwelskansrfat
    tfyqhladskndndniflsplsistafamtklgacndtlqqlmevfkfdtisektsdqih
    fffaklncrlyrkankasklvsanrlfgdksltfnetyqdiselvygaklqpldfkenae
    qsraainkwvsnktegritdvipseaineltvlvlvntiyfkglwkskfspentrkelfy
    kadgescsasmmyqegkfryrrvaegtqvlelpfkgdditmvlilpkpekslakvekelt
    pevlqewldeleemmlcvhmprfriedgfslkeqlqdmglvdlfspeksklpgivaegrd
    dlyvsdafhkaflevneegseaaastavviagrslnpnrvcfkanrpflvfirevplnti
    ifmgrvanpcvk
    

    Sequence, based on observed residues (ATOM records): (download)
    >2behI (I:)
    pvdictakprdipmnpmciyrspekkpeatnrrvwelskansrfattfyqhladskndnd
    niflsplsistafamtklgacndtlqqlmevfkfdtisektsdqihfffaklncrlyrka
    nkasklvsanrlfgdksltfnetyqdiselvygaklqpldfkenaeqsraainkwvsnkt
    egritdvipseaineltvlvlvntiyfkglwkskfspentrkelfykadgescsasmmyq
    egkfryrrvaegtqvlelpfkgdditmvlilpkpekslakvekeltpevlqewldeleem
    mlcvhmprfriedgfslkeqlqdmglvdlfspeksklpgivadlyvsdafhkaflevnee
    gseaaastavviagrslnpnrvcfkanrpflvfirevplntiifmgrvanpcv
    

  • Chain 'L':
    Sequence, based on SEQRES records: (download)
    >2behL (L:)
    hgspvdictakprdipmnpmciyrspekkatedegseqkipeatnrrvwelskansrfat
    tfyqhladskndndniflsplsistafamtklgacndtlqqlmevfkfdtisektsdqih
    fffaklncrlyrkankssklvsanrlfgdksltfnetyqdiselvygaklqpldfkenae
    qsraainkwvsnktegritdvipseaineltvlvlvntiyfkglwkskfspentrkelfy
    kadgescsasmmyqegkfryrrvaegtqvlelpfkgdditmvlilpkpekslakvekelt
    pevlqewldeleemmlvvhmprfriedgfslkeqlqdmglvdlfspeksklpgivaegrd
    dlyvsdafhkaflevneegseaaastavviagrslnpnrvtfkanrpflvfirevplnti
    ifmgrvanpcvk
    

    Sequence, based on observed residues (ATOM records): (download)
    >2behL (L:)
    vdictakprdipmnpmciyratnrrvwelskansrfattfyqhladskndndniflspls
    istafamtklgacndtlqqlmevfkfdtisetsdqihfffaklncrlyrkankssklvsa
    nrlfgdksltfnetyqdiselvygaklqpldfkenaeqsraainkwvsnktegritdvip
    seaineltvlvlvntiyfkglwkskfspentrkelfykadgescsasmmyqegkfryrrv
    aegtqvlelpfkgdditmvlilpkpekslakvekeltpevlqewldeleemmlvvhmprf
    riedgfslkeqlqdmglvdlfspeksklpgivaegrddlyvsdafhkaflevneegseaa
    astavviagrslnpnkanrpflvfirevplntiifmgrvanpc