PDB entry 2bc4

View 2bc4 on RCSB PDB site
Description: Crystal structure of HLA-DM
Class: immune system
Keywords: MHC class II, IMMUNE SYSTEM
Deposited on 2005-10-18, released 2006-05-23
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 2.27 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: HLA class II histocompatibility antigen, DM alpha chain
    Species: Homo sapiens [TaxId:9606]
    Gene: HLA-DMA, DMA, RING6
    Database cross-references and differences (RAF-indexed):
    • GB NP_006111
    Domains in SCOPe 2.08: d2bc4a1, d2bc4a2
  • Chain 'B':
    Compound: HLA class II histocompatibility antigen, DM beta chain
    Species: Homo sapiens [TaxId:9606]
    Gene: HLA-DMB, DMB, RING7
    Database cross-references and differences (RAF-indexed):
    • GB NP_002109
    Domains in SCOPe 2.08: d2bc4b1, d2bc4b2
  • Chain 'C':
    Compound: HLA class II histocompatibility antigen, DM alpha chain
    Species: Homo sapiens [TaxId:9606]
    Gene: HLA-DMA, DMA, RING6
    Database cross-references and differences (RAF-indexed):
    • GB NP_006111 (Start-202)
      • flag tag (203-205)
    Domains in SCOPe 2.08: d2bc4c1, d2bc4c2, d2bc4c3
  • Chain 'D':
    Compound: HLA class II histocompatibility antigen, DM beta chain
    Species: Homo sapiens [TaxId:9606]
    Gene: HLA-DMB, DMB, RING7
    Database cross-references and differences (RAF-indexed):
    • GB NP_002109
    Domains in SCOPe 2.08: d2bc4d1, d2bc4d2
  • Heterogens: CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2bc4A (A:)
vpeaptpmwpddlqnhtflhtvycqdgspsvglseaydedqlfffdfsqntrvprlpefa
dwaqeqgdapailfdkefcewmiqqigpkldgkipvsrgfpiaevftlkplefgkpntlv
cfvsnlfppmltvnwqhhsvpvegfgptfvsavdglsfqafsylnftpepsdifscivth
eidrytaiaywvprnalpsdlledykddddk

    Sequence, based on observed residues (ATOM records): (download) 
    >2bc4A (A:)
lqnhtflhtvycqdgspsvglseaydedqlfffdfsqntrvprlpefadwaqeqgdapai
lfdkefcewmiqqigpkldgkipvsrgfpiaevftlkplefgkpntlvcfvsnlfppmlt
vnwqhhsvpvegfgptfvsavdglsfqafsylnftpepsdifscivtheidrytaiaywv
prnalpsd

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2bc4B (B:)
ggfvahvestcllddagtpkdftycisfnkdlltcwdpeenkmapcefgvlnslanvlsq
hlnqkdtlmqrlrnglqncathtqpfwgsltnrtrppsvqvakttpfntrepvmlacyvw
gfypaevtitwrkngklvmphssahktaqpngdwtyqtlshlaltpsygdtytcvvehig
apepilrdwtpglspmqtlkkpptpppepet

    Sequence, based on observed residues (ATOM records): (download) 
    >2bc4B (B:)
fvahvestcllddagtpkdftycisfnkdlltcwdpeenkmapcefgvlnslanvlsqhl
nqkdtlmqrlrnglqncathtqpfwgsltnrtrppsvqvakttpfntrepvmlacyvwgf
ypaevtitwrkngklvmphssahktaqpngdwtyqtlshlaltpsygdtytcvvehigap
epilrdwtpgl

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2bc4C (C:)
vpeaptpmwpddlqnhtflhtvycqdgspsvglseaydedqlfffdfsqntrvprlpefa
dwaqeqgdapailfdkefcewmiqqigpkldgkipvsrgfpiaevftlkplefgkpntlv
cfvsnlfppmltvnwqhhsvpvegfgptfvsavdglsfqafsylnftpepsdifscivth
eidrytaiaywvprnalpsdlledykddddk

    Sequence, based on observed residues (ATOM records): (download) 
    >2bc4C (C:)
dlqnhtflhtvycqdgspsvglseaydedqlfffdfsqntrvprlpefadwaqeqgdapa
ilfdkefcewmiqqigpkldgkipvsrgfpiaevftlkplefgkpntlvcfvsnlfppml
tvnwqhhsvpvegfgptfvsavdglsfqafsylnftpepsdifscivtheidrytaiayw
vprnalpsdlledyk

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2bc4D (D:)
ggfvahvestcllddagtpkdftycisfnkdlltcwdpeenkmapcefgvlnslanvlsq
hlnqkdtlmqrlrnglqncathtqpfwgsltnrtrppsvqvakttpfntrepvmlacyvw
gfypaevtitwrkngklvmphssahktaqpngdwtyqtlshlaltpsygdtytcvvehig
apepilrdwtpglspmqtlkkpptpppepet

    Sequence, based on observed residues (ATOM records): (download) 
    >2bc4D (D:)
fvahvestcllddagtpkdftycisfnkdlltcwdpeenkmapcefgvlnslanvlsqhl
nqkdtlmqrlrnglqncathtqpfwgsltnrtrppsvqvakttpfntrepvmlacyvwgf
ypaevtitwrkngklvmphssahktaqpngdwtyqtlshlaltpsygdtytcvvehigap
epilrdwtpglspmqtl