PDB entry 2b8t

View 2b8t on RCSB PDB site
Description: Crystal structure of Thymidine Kinase from U.urealyticum in complex with thymidine
Class: transferase
Keywords: deoxyribonucleoside kinase, zinc-binding domain, tk1, uu-tk, thymidine, transferase
Deposited on 2005-10-10, released 2005-12-20
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-10-11, with a file datestamp of 2017-10-06.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Thymidine kinase
    Species: Ureaplasma parvum [TaxId:134821]
    Gene: tdk
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9PPP5
      • engineered (15)
    Domains in SCOPe 2.08: d2b8ta1, d2b8ta2
  • Chain 'B':
    Compound: Thymidine kinase
    Species: Ureaplasma parvum [TaxId:134821]
    Gene: tdk
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9PPP5
      • engineered (15)
    Domains in SCOPe 2.08: d2b8tb1, d2b8tb2
  • Chain 'C':
    Compound: Thymidine kinase
    Species: Ureaplasma parvum [TaxId:134821]
    Gene: tdk
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9PPP5
      • engineered (15)
    Domains in SCOPe 2.08: d2b8tc1, d2b8tc2
  • Chain 'D':
    Compound: Thymidine kinase
    Species: Ureaplasma parvum [TaxId:134821]
    Gene: tdk
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9PPP5
      • engineered (15)
    Domains in SCOPe 2.08: d2b8td1, d2b8td2
  • Heterogens: ZN, THM, TRS, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2b8tA (A:)
makvnafskkigwiefitgpmfagktaelirrlhrleyadvkylvfkpkidtrsirniqs
rtgtslpsvevesapeilnyimsnsfndetkvigidevqffddricevanilaengfvvi
isgldknfkgepfgpiaklftyadkitkltaicnecgaeathslrkidgkhadynddivk
igcqefysavcrhhhkvpnrpylnsnseefikffknkkrnkni

    Sequence, based on observed residues (ATOM records): (download) 
    >2b8tA (A:)
igwiefitgpmfagktaelirrlhrleyadvkylvfkpkidtrsirniqsrtgtslpsve
vesapeilnyimsnsfndetkvigidevqffddricevanilaengfvviisgldknfkg
epfgpiaklftyadkitkltaicnecgaeathslrkidgkhadynddivkigcqefysav
crhhhkvpnrpylnsnseefikffkn

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2b8tB (B:)
makvnafskkigwiefitgpmfagktaelirrlhrleyadvkylvfkpkidtrsirniqs
rtgtslpsvevesapeilnyimsnsfndetkvigidevqffddricevanilaengfvvi
isgldknfkgepfgpiaklftyadkitkltaicnecgaeathslrkidgkhadynddivk
igcqefysavcrhhhkvpnrpylnsnseefikffknkkrnkni

    Sequence, based on observed residues (ATOM records): (download) 
    >2b8tB (B:)
igwiefitgpmfagktaelirrlhrleyadvkylvfkpkilpsvevesapeilnyimsns
fndetkvigidevqffddricevanilaengfvviisgldknfkgepfgpiaklftyadk
itkltaicnecgaeathslrkidgkhadynddivkigcqefysavcrhhhkvpnrpylns
nseefikff

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2b8tC (C:)
makvnafskkigwiefitgpmfagktaelirrlhrleyadvkylvfkpkidtrsirniqs
rtgtslpsvevesapeilnyimsnsfndetkvigidevqffddricevanilaengfvvi
isgldknfkgepfgpiaklftyadkitkltaicnecgaeathslrkidgkhadynddivk
igcqefysavcrhhhkvpnrpylnsnseefikffknkkrnkni

    Sequence, based on observed residues (ATOM records): (download) 
    >2b8tC (C:)
igwiefitgpmfagktaelirrlhrleyadvkylvfkpkidsrtgtslpsvevesapeil
nyimsnsfndetkvigidevqffddricevanilaengfvviisgldknfkgepfgpiak
lftyadkitkltaicnecgaeathslrkidgkhadynddivkigcqefysavcrhhhkvp
nrpylnsnseefikffknk

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2b8tD (D:)
makvnafskkigwiefitgpmfagktaelirrlhrleyadvkylvfkpkidtrsirniqs
rtgtslpsvevesapeilnyimsnsfndetkvigidevqffddricevanilaengfvvi
isgldknfkgepfgpiaklftyadkitkltaicnecgaeathslrkidgkhadynddivk
igcqefysavcrhhhkvpnrpylnsnseefikffknkkrnkni

    Sequence, based on observed residues (ATOM records): (download) 
    >2b8tD (D:)
gwiefitgpmfagktaelirrlhrleyadvkylvfkpksirniqsrtgtslpsvevesap
eilnyimsnsfndetkvigidevqffddricevanilaengfvviisgldknfkgepfgp
iaklftyadkitkltaicnecgaeathslrkidgkhadynddivkigcqefysavcrhhh
kvpnrpylnsnseefikffknkkr