PDB entry 2b7o
View 2b7o on RCSB PDB site
Description: The Structure of 3-Deoxy-D-Arabino-Heptulosonate 7-Phosphate Synthase from Mycobacterium tuberculosis
Class: transferase
Keywords: Mycobacterium tuberculosis, DAH7PS synthase, Shikimate pathway, aromatic biosynthesis, evolutionary relationships, Structural Genomics, Mycobacterium Tuberculosis Structural Proteomics Project, XMTB
Deposited on
2005-10-05, released
2005-10-18
The last revision prior to the SCOP 1.73 freeze date was dated
2006-12-05, with a file datestamp of
2007-06-04.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.19
AEROSPACI score: 0.36
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase arog
Species: Mycobacterium tuberculosis
Gene: Rv2178c
Database cross-references and differences (RAF-indexed):
- Uniprot O53512 (2-463)
- cloning artifact (0-1)
- modified residue (2)
- modified residue (49)
- modified residue (93)
- modified residue (110)
- modified residue (120)
- modified residue (152)
- modified residue (181)
- modified residue (229)
- modified residue (259)
- modified residue (312)
- modified residue (339)
- modified residue (369)
- modified residue (460)
Domains in SCOP 1.73: d2b7oa1 - Chain 'B':
Compound: 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase arog
Species: Mycobacterium tuberculosis
Gene: Rv2178c
Database cross-references and differences (RAF-indexed):
- Uniprot O53512 (2-463)
- cloning artifact (0-1)
- modified residue (2)
- modified residue (49)
- modified residue (93)
- modified residue (110)
- modified residue (120)
- modified residue (152)
- modified residue (181)
- modified residue (229)
- modified residue (259)
- modified residue (312)
- modified residue (339)
- modified residue (369)
- modified residue (460)
Domains in SCOP 1.73: d2b7ob1 - Heterogens: MN, SO4, PEP, CE1, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>2b7oA (A:)
gamnwtvdipidqlpslpplptdlrtrldaalakpaaqqptwpadqalamrtvlesvppv
tvpseivrlqeqlaqvakgeafllqggdcaetfmdntephirgnvrallqmavvltygas
mpvvkvariagqyakprsadidalglrsyrgdmingfapdaaarehdpsrlvrayanasa
amnlvraltssglaslhlvhdwnrefvrtspagaryealateidrglrfmsacgvadrnl
qtaeiyashealvldyeramlrlsdgddgepqlfdlsahtvwigertrqidgahiafaqv
ianpvgvklgpnmtpelaveyverldphnkpgrltlvsrmgnhkvrdllppivekvqatg
hqviwqcdpmhgnthesstgfktrhfdrivdevqgffevhralgthpggihveitgenvt
eclggaqdisetdlagryetacdprlntqqslelaflvaemlrd
Sequence, based on observed residues (ATOM records): (download)
>2b7oA (A:)
gamnwtvdipidqlpslpplptdlrtrldaalakpaaqqptwpadqalamrtvlesvppv
tvpseivrlqeqlaqvakgeafllqggdcaetfmdntephirgnvrallqmavvltygas
mpvvkvariagqyakprsadidalglrsyrgdmingfapdaaarehdpsrlvrayanasa
amnlvraltssglaslhlvhdwnrefvrtspagaryealateidrglrfmsacgvadrnl
qtaeiyashealvldyeramlrlsdgddgepqlfdlsahtvwigertrqidgahiafaqv
ianpvgvklgpnmtpelaveyverldphnkpgrltlvsrmgnhkvrdllppivekvqatg
hqviwqcdpmhgnthesstgfktrhfdrivdevqgffevhralgthpggihveitgenvt
lagryetacdprlntqqslelaflvaemlrd
- Chain 'B':
Sequence, based on SEQRES records: (download)
>2b7oB (B:)
gamnwtvdipidqlpslpplptdlrtrldaalakpaaqqptwpadqalamrtvlesvppv
tvpseivrlqeqlaqvakgeafllqggdcaetfmdntephirgnvrallqmavvltygas
mpvvkvariagqyakprsadidalglrsyrgdmingfapdaaarehdpsrlvrayanasa
amnlvraltssglaslhlvhdwnrefvrtspagaryealateidrglrfmsacgvadrnl
qtaeiyashealvldyeramlrlsdgddgepqlfdlsahtvwigertrqidgahiafaqv
ianpvgvklgpnmtpelaveyverldphnkpgrltlvsrmgnhkvrdllppivekvqatg
hqviwqcdpmhgnthesstgfktrhfdrivdevqgffevhralgthpggihveitgenvt
eclggaqdisetdlagryetacdprlntqqslelaflvaemlrd
Sequence, based on observed residues (ATOM records): (download)
>2b7oB (B:)
gamnwtvdipidqlpslpplptdlrtrldaalakpaaqqptwpadqalamrtvlesvppv
tvpseivrlqeqlaqvakgeafllqggdcaetfmdntephirgnvrallqmavvltygas
mpvvkvariagqyakprsadidalglrsyrgdmingfapdaaarehdpsrlvrayanasa
amnlvraltssglaslhlvhdwnrefvrtspagaryealateidrglrfmsacgvadrnl
qtaeiyashealvldyeramlrlsdgddgepqlfdlsahtvwigertrqidgahiafaqv
ianpvgvklgpnmtpelaveyverldphnkpgrltlvsrmgnhkvrdllppivekvqatg
hqviwqcdpmhgnthesfktrhfdrivdevqgffevhralgthpggihveitgenvtecl
lagryetacdprlntqqslelaflvaemlrd