PDB entry 2b4x

View 2b4x on RCSB PDB site
Description: Crystal Structure of Antithrombin-III
Class: blood clotting
Keywords: serpin; inhibitor; coagulation; protease, BLOOD CLOTTING
Deposited on 2005-09-27, released 2006-10-10
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-25.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.228
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'I':
    Compound: antithrombin-III
    Species: Homo sapiens [TaxId:9606]
    Gene: SERPINC1, AT3
    Database cross-references and differences (RAF-indexed):
    • Uniprot P01008 (0-426)
      • engineered (215)
    Domains in SCOPe 2.07: d2b4xi1
  • Chain 'L':
    Compound: antithrombin-III
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2b4xl_
  • Heterogens: NAG, HOH

PDB Chain Sequences:

  • Chain 'I':
    Sequence, based on SEQRES records: (download)
    >2b4xI (I:)
    vdictakprdipmnpmciyrspekkatedegseqkipeatnrrvwelskansrfattfyq
    hladskndndniflsplsistafamtklgacndtlqqlmevfkfdtisektsdqihfffa
    klncrlyrkaakssklvsanrlfgdksltfnetyqdiselvygaklqpldfkenaeqsra
    ainkwvsnktegritdvipseaineltvlvlvntilfkglwkskfspentrkelfykadg
    escsasmmyqegkfryrrvaegtqvlelpfkgdditmvlilpkpekslakvekeltpevl
    qewldeleemmlvvhmprfriedgfslkeqlqdmglvdlfspeksklpgivaegrddlyv
    sdafhkaflevneegseaaastavviagrslnpnrvtfkanrpflvfirevplntiifmg
    rvanpcv
    

    Sequence, based on observed residues (ATOM records): (download)
    >2b4xI (I:)
    vdictakprdipmnpmciyrspekkeqkipeatnrrvwelskansrfattfyqhladskn
    dndniflsplsistafamtklgacndtlqqlmevfkfdtisektsdqihfffaklncrly
    rkkssklvsanrlfgdksltfnetyqdiselvygaklqpldfkenaeqsraainkwvsnk
    tegritdvipseaineltvlvlvntilfkglwkskfspentrkelfykadgescsasmmy
    qegkfryrrvaegtqvlelpfkgdditmvlilpkpekslakvekeltpevlqewldelee
    mmlvvhmprfriedgfslkeqlqdmglvdlfspeksklpgiddlyvsdafhkaflevnee
    gseaaastavviagrslnpnrvtfkanrpflvfirevplntiifmgrvanpcv
    

  • Chain 'L':
    Sequence, based on SEQRES records: (download)
    >2b4xL (L:)
    vdictakprdipmnpmciyrspekkatedegseqkipeatnrrvwelskansrfattfyq
    hladskndndniflsplsistafamtklgacndtlqqlmevfkfdtisektsdqihfffa
    klncrlyrkankssklvsanrlfgdksltfnetyqdiselvygaklqpldfkenaeqsra
    ainkwvsnktegritdvipseaineltvlvlvntiyfkglwkskfspentrkelfykadg
    escsasmmyqegkfryrrvaegtqvlelpfkgdditmvlilpkpekslakvekeltpevl
    qewldeleemmlvvhmprfriedgfslkeqlqdmglvdlfspeksklpgivaegrddlyv
    sdafhkaflevneegseaaastavviagrslnpnrvtfkanrpflvfirevplntiifmg
    rvanpcv
    

    Sequence, based on observed residues (ATOM records): (download)
    >2b4xL (L:)
    vdictakprdipmnpmciyrspatnrrvwelskansrfattfyqhladskndndniflsp
    lsistafamtklgacndtlqqlmevfkfdtisektsdqihfffaklncrlyrkanksskl
    vsanrlfgdksltfnetyqdiselvygaklqpldfkenaeqsraainkwvsnktegritd
    vipseaineltvlvlvntiyfkglwkskfspentrkelfykadgescsasmmyqegkfry
    rrvaegtqvlelpfkgdditmvlilpkpekslakvekeltpevlqewldeleemmlvvhm
    prfriedgfslkeqlqdmglvdlfspeksklpgivaegrddlyvsdafhkaflevneegs
    eaaastavviagrslpnrvtfkanrpflvfirevplntiifmgrvanpcv