PDB entry 2b2v

View 2b2v on RCSB PDB site
Description: Crystal structure analysis of human CHD1 chromodomains 1 and 2 bound to histone H3 resi 1-15 MeK4
Class: peptide binding protein
Keywords: CHD, Chromodomain, three stranded antiparallel Beta sheet, alpha helix linker, histone H3, monomethyllysine
Deposited on 2005-09-19, released 2005-12-27
The last revision prior to the SCOP 1.75 freeze date was dated 2005-12-27, with a file datestamp of 2007-06-28.
Experiment type: XRAY
Resolution: 2.65 Å
R-factor: 0.216
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Chromodomain-helicase-DNA-binding protein 1
    Species: HOMO SAPIENS
    Gene: CHD1
    Database cross-references and differences (RAF-indexed):
    • Uniprot O14646 (Start-184)
      • cloning artifact (185)
    Domains in SCOP 1.75: d2b2va1, d2b2va2
  • Chain 'B':
    Compound: Chromodomain-helicase-DNA-binding protein 1
    Species: HOMO SAPIENS
    Gene: CHD1
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2b2vb1, d2b2vb2
  • Chain 'C':
    Compound: Chromodomain-helicase-DNA-binding protein 1
    Species: HOMO SAPIENS
    Gene: CHD1
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2b2vc1
  • Chain 'D':
    Compound: histone h3
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • Uniprot P68431 (0-End)
      • modified residue (3)
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2b2vA (A:)
mkkhhhhhheeefetierfmdcrigrkgatgatttiyaveadgdpnagfeknkepgeiqy
likwkgwshihntweteetlkqqnvrgmkkldnykkkdqetkrwlknaspedveyyncqq
eltddlhkqyqivgriiahsnqksaagypdyyckwqglpysecswedgaliskkfqacid
eyfsrkk

    Sequence, based on observed residues (ATOM records): (download) 
    >2b2vA (A:)
efetierfmdcrigrkgatgatttiyaveadgdpnagfeknkepgeiqylikwkgwshih
ntweteetlkqqnvrgmkkldnykkkdqetkrwlknaspedveyyncqqeltddlhkqyq
ivgriiahsnqksaagypdyyckwqglpysecswedgaliskkfqacideyfsrk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2b2vB (B:)
mkkhhhhhheeefetierfmdcrigrkgatgatttiyaveadgdpnagfeknkepgeiqy
likwkgwshihntweteetlkqqnvrgmkkldnykkkdqetkrwlknaspedveyyncqq
eltddlhkqyqivgriiahsnqksaagypdyyckwqglpysecswedgaliskkfqacid
eyfsrkk

    Sequence, based on observed residues (ATOM records): (download) 
    >2b2vB (B:)
fetierfmdcrigrkgatgatttiyaveadgdpnagfeknkepgeiqylikwkgwshihn
tweteetlkqqnvrgmkkldnykkkdqetkrwlknaspedveyyncqqeltddlhkqyqi
vgriiahsnqkgypdyyckwqglpysecswedgaliskkfqacideyfsr

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2b2vC (C:)
mkkhhhhhheeefetierfmdcrigrkgatgatttiyaveadgdpnagfeknkepgeiqy
likwkgwshihntweteetlkqqnvrgmkkldnykkkdqetkrwlknaspedvey

    Sequence, based on observed residues (ATOM records): (download) 
    >2b2vC (C:)
fetierfmdcrigrkgatgatttiyaveadgdpnagfeknkepgeiqylikwkgwshihn
tweteetlkqqnvrgmkkldnykkk

  • Chain 'D':
    No sequence available.