PDB entry 2b2t

View 2b2t on RCSB PDB site
Description: Tandem chromodomains of human CHD1 complexed with Histone H3 Tail containing trimethyllysine 4 and phosphothreonine 3
Class: peptide binding protein
Keywords: CHD, Chromodomain, three stranded antiparallel Beta sheet, alpha helix linker, histone H3, trimethyllysine, phosphothreonine
Deposited on 2005-09-19, released 2005-12-27
The last revision prior to the SCOP 1.75 freeze date was dated 2005-12-27, with a file datestamp of 2007-06-28.
Experiment type: XRAY
Resolution: 2.45 Å
R-factor: 0.218
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Chromodomain-helicase-DNA-binding protein 1
    Species: HOMO SAPIENS
    Gene: CHD1
    Database cross-references and differences (RAF-indexed):
    • Uniprot O14646 (Start-184)
      • modified residue (19)
      • modified residue (87)
      • see remark 999 (177)
      • cloning artifact (185)
    Domains in SCOP 1.75: d2b2ta1, d2b2ta2
  • Chain 'B':
    Compound: Chromodomain-helicase-DNA-binding protein 1
    Species: HOMO SAPIENS
    Gene: CHD1
    Database cross-references and differences (RAF-indexed):
    • Uniprot O14646 (9-184)
      • modified residue (19)
      • modified residue (87)
      • see remark 999 (177)
      • cloning artifact (185)
    Domains in SCOP 1.75: d2b2tb1, d2b2tb2
  • Chain 'C':
    Compound: Chromodomain-helicase-DNA-binding protein 1
    Species: HOMO SAPIENS
    Gene: CHD1
    Database cross-references and differences (RAF-indexed):
    • Uniprot O14646
      • modified residue (19)
      • modified residue (87)
    Domains in SCOP 1.75: d2b2tc1
  • Chain 'D':
    Compound: Histone H3 tail
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • Uniprot P68431 (0-End)
      • modified residue (2-3)
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2b2tA (A:)
mkkhhhhhheeefetierfmdcrigrkgatgatttiyaveadgdpnagfeknkepgeiqy
likwkgwshihntweteetlkqqnvrgmkkldnykkkdqetkrwlknaspedveyyncqq
eltddlhkqyqivgriiahsnqksaagypdyyckwqglpysecswedgaliskkfqamid
eyfsrkk

    Sequence, based on observed residues (ATOM records): (download) 
    >2b2tA (A:)
eefetierfmdcrigrkgatgatttiyaveadgdpnagfeknkepgeiqylikwkgwshi
hntweteetlkqqnvrgmkkldnykkkdqetkrwlknaspedveyyncqqeltddlhkqy
qivgriiahsnqksaagypdyyckwqglpysecswedgaliskkfqamideyfsrk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2b2tB (B:)
mkkhhhhhheeefetierfmdcrigrkgatgatttiyaveadgdpnagfeknkepgeiqy
likwkgwshihntweteetlkqqnvrgmkkldnykkkdqetkrwlknaspedveyyncqq
eltddlhkqyqivgriiahsnqksaagypdyyckwqglpysecswedgaliskkfqamid
eyfsrkk

    Sequence, based on observed residues (ATOM records): (download) 
    >2b2tB (B:)
eeefetierfmdcrigrkgatgatttiyaveadgdpnagfekkepgeiqylikwkgwshi
hntweteetlkqqnvrgmkkldnykkkdqetkrwlknaspedveyyncqqeltddlhkqy
qivgriiahsnqksgypdyyckwqglpysecswedgaliskkfqamideyfsrk

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2b2tC (C:)
mkkhhhhhheeefetierfmdcrigrkgatgatttiyaveadgdpnagfeknkepgeiqy
likwkgwshihntweteetlkqqnvrgmkkldnykkkdqetkrwlknaspedvey

    Sequence, based on observed residues (ATOM records): (download) 
    >2b2tC (C:)
efetierfmdcrigrkgatgatttiyaveadgdpnagfeknkepgeiqylikwkgwshih
ntweteetlkqqnvrgmkkldnykkk

  • Chain 'D':
    No sequence available.