PDB entry 2aw2

View 2aw2 on RCSB PDB site
Description: Crystal structure of the human BTLA-HVEM complex
Class: immune system
Keywords: IgI domain, IgG domain, TNFRSF, protein-protein complex, IMMUNE SYSTEM
Deposited on 2005-08-31, released 2005-09-27
The last revision prior to the SCOPe 2.05 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.236
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: B and T lymphocyte attenuator
    Species: Homo sapiens [TaxId:9606]
    Gene: BTLA
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q7Z6A9 (Start-111)
      • expression tag (112-117)
    Domains in SCOPe 2.05: d2aw2a1
  • Chain 'B':
    Compound: Tumor necrosis factor receptor superfamily member 14
    Species: Homo sapiens [TaxId:9606]
    Gene: TNFRSF14, HVEA, HVEM
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d2aw2b1, d2aw2b2
  • Chain 'X':
    Compound: B and T lymphocyte attenuator
    Species: Homo sapiens [TaxId:9606]
    Gene: BTLA
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q7Z6A9 (Start-111)
      • expression tag (112-114)
    Domains in SCOPe 2.05: d2aw2x_
  • Chain 'Y':
    Compound: Tumor necrosis factor receptor superfamily member 14
    Species: Homo sapiens [TaxId:9606]
    Gene: TNFRSF14, HVEA, HVEM
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d2aw2y1, d2aw2y2
  • Heterogens: NI, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2aw2A (A:)
wnihgkescdvqlyikrqsehsilagdpfelecpvkycanrphvtwcklngttcvkledr
qtswkeeknisffilhfepvlpndngsyrcsanfqsnlieshsttlyvtdvkhhhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2aw2A (A:)
cdvqlyikrqsehsilagdpfelecpvkycanrphvtwcklngttcvkledrqtswkeek
nisffilhfepvlpndngsyrcsanfqsnlieshsttlyvtdvkhhhhhh

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2aw2B (B:)
gshmlpsckedeypvgseccpkcspgyrvkeacgeltgtvcepcppgtyiahlnglskcl
qcqmcdpamglrasrncsrtenavcgcspghfcivqdgdhcaacraya

    Sequence, based on observed residues (ATOM records): (download) 
    >2aw2B (B:)
psckedeypvgseccpkcspgyrvkeacgeltgtvcepcppgtyiahlnglskclqcqmc
dpamglrasrncsrtenavcgcspghfcivqdhcaacray

  • Chain 'X':
    Sequence, based on SEQRES records: (download) 
    >2aw2X (X:)
wnihgkescdvqlyikrqsehsilagdpfelecpvkycanrphvtwcklngttcvkledr
qtswkeeknisffilhfepvlpndngsyrcsanfqsnlieshsttlyvtdvkhhhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2aw2X (X:)
cdvqlyikrqsehsilagdpfelecpvkycanrphvtwcklngttcvkledrqtswkeek
nisffilhfepvlpndngsyrcsanfqsnlieshsttlyvtdvkhhh

  • Chain 'Y':
    Sequence, based on SEQRES records: (download) 
    >2aw2Y (Y:)
gshmlpsckedeypvgseccpkcspgyrvkeacgeltgtvcepcppgtyiahlnglskcl
qcqmcdpamglrasrncsrtenavcgcspghfcivqdgdhcaacraya

    Sequence, based on observed residues (ATOM records): (download) 
    >2aw2Y (Y:)
psckedeypvgseccpkcspgyrvkeacgeltgtvcepcppgtyiahlnglskclqcqmc
dpamglrasrncsrtenavcgcspghfcivqdhcaacray