PDB entry 2aw2

View 2aw2 on RCSB PDB site
Description: Crystal structure of the human BTLA-HVEM complex
Class: immune system
Keywords: IgI domain, IgG domain, TNFRSF, protein-protein complex
Deposited on 2005-08-31, released 2005-09-27
The last revision prior to the SCOP 1.73 freeze date was dated 2005-12-06, with a file datestamp of 2007-06-28.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.236
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: B and T lymphocyte attenuator
  Species: HOMO SAPIENS
  Gene: BTLA
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q7Z6A9 (Start-111)
    • his tag (112-117)
• Chain 'B':
  Compound: Tumor necrosis factor receptor superfamily member 14
  Species: HOMO SAPIENS
  Gene: TNFRSF14, HVEA, HVEM
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q92956
  Domains in SCOP 1.73: d2aw2b1, d2aw2b2
• Chain 'X':
  Compound: B and T lymphocyte attenuator
  Species: HOMO SAPIENS
  Gene: BTLA
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q7Z6A9 (Start-111)
    • his tag (112-114)
• Chain 'Y':
  Compound: Tumor necrosis factor receptor superfamily member 14
  Species: HOMO SAPIENS
  Gene: TNFRSF14, HVEA, HVEM
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q92956
  Domains in SCOP 1.73: d2aw2y1, d2aw2y2
• Heterogens: NI, HOH

PDB Chain Sequences:

• Chain 'A':
  No sequence available.
  
  
• Chain 'B':
  Sequence, based on SEQRES records: (download)
  

  >2aw2B (B:)
  gshmlpsckedeypvgseccpkcspgyrvkeacgeltgtvcepcppgtyiahlnglskcl
  qcqmcdpamglrasrncsrtenavcgcspghfcivqdgdhcaacraya
  

  
  Sequence, based on observed residues (ATOM records): (download)
  

  >2aw2B (B:)
  psckedeypvgseccpkcspgyrvkeacgeltgtvcepcppgtyiahlnglskclqcqmc
  dpamglrasrncsrtenavcgcspghfcivqdhcaacray
  

  
  
• Chain 'X':
  No sequence available.
  
  
• Chain 'Y':
  Sequence, based on SEQRES records: (download)
  

  >2aw2Y (Y:)
  gshmlpsckedeypvgseccpkcspgyrvkeacgeltgtvcepcppgtyiahlnglskcl
  qcqmcdpamglrasrncsrtenavcgcspghfcivqdgdhcaacraya
  

  
  Sequence, based on observed residues (ATOM records): (download)
  

  >2aw2Y (Y:)
  psckedeypvgseccpkcspgyrvkeacgeltgtvcepcppgtyiahlnglskclqcqmc
  dpamglrasrncsrtenavcgcspghfcivqdhcaacray