PDB entry 2arv

View 2arv on RCSB PDB site
Description: Structure of human Activin A
Class: hormone/growth factor
Keywords: homodimer,cystine knot, disulfide linked
Deposited on 2005-08-22, released 2006-03-07
The last revision prior to the SCOP 1.73 freeze date was dated 2006-03-28, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.218
AEROSPACI score: 0.39 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Inhibin beta A chain
    Species: HOMO SAPIENS
    Gene: INHBA
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d2arva1
  • Chain 'B':
    Compound: Inhibin beta A chain
    Species: HOMO SAPIENS
    Gene: INHBA
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d2arvb1
  • Heterogens: SO4, 1PG, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >2arvA (A:)
    glecdgkvnicckkqffvsfkdigwndwiiapsgyhanycegecpshiagtsgsslsfhs
    tvinhyrmrghspfanlksccvptklrpmsmlyyddgqniikkdiqnmiveecgcs
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >2arvB (B:)
    glecdgkvnicckkqffvsfkdigwndwiiapsgyhanycegecpshiagtsgsslsfhs
    tvinhyrmrghspfanlksccvptklrpmsmlyyddgqniikkdiqnmiveecgcs
    

    Sequence, based on observed residues (ATOM records): (download)
    >2arvB (B:)
    glecdgkvnicckkqffvsfkdigwndwiiapsgyhanycegecpssfhstvinhyrmrg
    hspfanlksccvptklrpmsmlyyddgqniikkdiqnmiveecgcs