PDB entry 2arv

View 2arv on RCSB PDB site
Description: Structure of human Activin A
Class: hormone/growth factor
Keywords: homodimer,cystine knot, disulfide linked, HORMONE-GROWTH FACTOR COMPLEX
Deposited on 2005-08-22, released 2006-03-07
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-25.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.218
AEROSPACI score: 0.39 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Inhibin beta A chain
    Species: Homo sapiens [TaxId:9606]
    Gene: INHBA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2arva_
  • Chain 'B':
    Compound: Inhibin beta A chain
    Species: Homo sapiens [TaxId:9606]
    Gene: INHBA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2arvb_
  • Heterogens: SO4, 1PG, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >2arvA (A:)
    glecdgkvnicckkqffvsfkdigwndwiiapsgyhanycegecpshiagtsgsslsfhs
    tvinhyrmrghspfanlksccvptklrpmsmlyyddgqniikkdiqnmiveecgcs
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >2arvB (B:)
    glecdgkvnicckkqffvsfkdigwndwiiapsgyhanycegecpshiagtsgsslsfhs
    tvinhyrmrghspfanlksccvptklrpmsmlyyddgqniikkdiqnmiveecgcs
    

    Sequence, based on observed residues (ATOM records): (download)
    >2arvB (B:)
    glecdgkvnicckkqffvsfkdigwndwiiapsgyhanycegecpssfhstvinhyrmrg
    hspfanlksccvptklrpmsmlyyddgqniikkdiqnmiveecgcs