PDB entry 2aoi

View 2aoi on RCSB PDB site
Description: Crystal structure analysis of HIV-1 protease with a substrate analog P1-P6
Class: hydrolase
Keywords: hiv-1 protease, mutant, dimer, substrate analog
Deposited on 2005-08-12, released 2006-01-17
The last revision prior to the SCOP 1.73 freeze date was dated 2006-01-17, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 1.4 Å
R-factor: 0.159
AEROSPACI score: 0.7 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: Pol polyprotein
  Species: HUMAN IMMUNODEFICIENCY VIRUS TYPE 1
  Gene: pol
  Database cross-references and differences (RAF-indexed):
  • Uniprot P04587
    • engineered (6)
    • engineered (32)
    • engineered (62)
    • engineered (66)
    • engineered (94)
  Domains in SCOP 1.73: d2aoia1
• Chain 'B':
  Compound: Pol polyprotein
  Species: HUMAN IMMUNODEFICIENCY VIRUS TYPE 1
  Gene: pol
  Database cross-references and differences (RAF-indexed):
  • Uniprot P04587 (0-98)
    • engineered (6)
    • engineered (32)
    • engineered (62)
    • engineered (66)
    • engineered (94)
  Domains in SCOP 1.73: d2aoib1
• Chain 'C':
  Compound: peptide inhibitor
  Species: synthetic, synthetic
  
• Heterogens: SO4, NH2, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >2aoiA (A:)
  pqitlwkrplvtikiggqlkealldtgaddtvieemslpgrwkpkmiggiggfikvrqyd
  qiiieiaghkaigtvlvgptpvniigrnlltqigatlnf
  

  
  
• Chain 'B':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >2aoiB (B:)
  pqitlwkrplvtikiggqlkealldtgaddtvieemslpgrwkpkmiggiggfikvrqyd
  qiiieiaghkaigtvlvgptpvniigrnlltqigatlnf
  

  
  
• Chain 'C':
  No sequence available.