PDB entry 2any
View 2any on RCSB PDB site
Description: Expression, Crystallization and the Three-dimensional Structure of the Catalytic Domain of Human Plasma Kallikrein: Implications for Structure-Based Design of Protease Inhibitors
Class: blood clotting, hydrolase
Keywords: mutagenically deglycosyalted human plasma kallikrein protease domain; trypsin-like serine protease, BLOOD CLOTTING, HYDROLASE
Deposited on
2005-08-11, released
2005-10-11
The last revision prior to the SCOPe 2.08 freeze date was dated
2017-10-11, with a file datestamp of
2017-10-06.
Experiment type: XRAY
Resolution: 1.4 Å
R-factor: N/A
AEROSPACI score: 0.53
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: plasma kallikrein, light chain
Species: Homo sapiens [TaxId:9606]
Gene: KLKB1, KLK3
Database cross-references and differences (RAF-indexed):
- Uniprot P03952 (0-End)
- engineered (5)
- engineered (62)
- engineered (103)
- engineered (112)
Domains in SCOPe 2.08: d2anya_ - Heterogens: PO4, BAM, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>2anyA (A:)
ivggtesswgewpwqvslqvkltaqrhlcggslighqwvltaahcfdglplqdvwriysg
ilelsditkdtpfsqikeiiihqnykvsegnhdialiklqapleytefqkpislpskgdt
stiytncwvtgwgfskekgeiqnilqkvniplvtneecqkryqdykitqrmvcagykegg
kdackgdsggplvckhngmwrlvgitswgegcarreqpgvytkvaeymdwilektqssdg
k
Sequence, based on observed residues (ATOM records): (download)
>2anyA (A:)
ivggtesswgewpwqvslqvkltaqrhlcggslighqwvltaahcfdglplqdvwriysg
ilelsditkdtpfsqikeiiihqnykvsegnhdialiklqapleytefqkpislpskgdt
stiytncwvtgwgfskekgeiqnilqkvniplvtneecqkryqdykitqrmvcagykegg
kdackgdsggplvckhngmwrlvgitswgegcarreqpgvytkvaeymdwilektqss