PDB entry 2ajq

View 2ajq on RCSB PDB site
Description: Structure of replicative DNA polymerase provides insigts into the mechanisms for processivity, frameshifting and editing
Class: transferase,transcription/DNA
Keywords: Polymerase T7; x-ray crystallography; ternary complex, TRANSFERASE, TRANSCRIPTION/DNA COMPLEX, TRANSFERASE,TRANSCRIPTION/DNA COMPLEX
Deposited on 2005-08-02, released 2006-09-26
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-11-17, with a file datestamp of 2009-11-13.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.233
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: T7 DNA polymerase
    Species: Enterobacteria phage T7 [TaxId:10760]
    Gene: 5
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00581 (0-703)
      • engineered (4)
      • engineered (6)
    Domains in SCOPe 2.07: d2ajqa1, d2ajqa2
  • Chain 'B':
    Compound: Thioredoxin 1
    Species: Escherichia coli [TaxId:562]
    Gene: trxA, fipA, tsnC
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2ajqb_
  • Chain 'F':
    Compound: T7 DNA polymerase
    Species: Enterobacteria phage T7 [TaxId:10760]
    Gene: 5
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00581 (0-703)
      • engineered (4)
      • engineered (6)
    Domains in SCOPe 2.07: d2ajqf1, d2ajqf2
  • Chain 'I':
    Compound: Thioredoxin 1
    Species: Escherichia coli [TaxId:562]
    Gene: trxA, fipA, tsnC
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2ajqi_
  • Chain 'P':
    Compound: DNA Primer
  • Chain 'T':
    Compound: DNA Template
  • Chain 'X':
    Compound: DNA Primer
  • Chain 'Z':
    Compound: DNA Template
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2ajqA (A:)
mivsaiaanallesvtkfhcgviydystaeyvsyrpsdfgayldaleaevargglivfhn
ghkydvpaltklaklqlnrefhlprencidtlvlsrlihsnlkdtdmgllrsgklpgkrf
gshaleawgyrlgemkgeykddfkrmleeqgeeyvdgmewwnfneemmdynvqdvvvtka
llekllsdkhyfppeidftdvgyttfwsesleavdiehraawllakqerngfpfdtkaie
elyvelaarrsellrkltetfgswyqpkggtemfchprtgkplpkypriktpkvggifkk
pknkaqregrepceldtreyvagapytpvehvvfnpssrdhiqkklqeagwvptkytdkg
apvvddevlegvrvddpekqaaidlikeylmiqkrigqsaegdkawlryvaedgkihgsv
npngavtgrathafpnlaqipgvrspygeqcraafgaehhldgitgkpwvqagidasgle
lrclahfmarfdngeyaheilngdihtknqiaaelptrdnaktfiygflygagdekigqi
vgagkergkelkkkflentpaiaalresiqqtlvessqwvageqqvkwkrrwikgldgrk
vhvrsphaalntllqsagalicklwiikteemlvekglkhgwdgdfaymawvhdeiqvgc
rteeiaqvvietaqeamrwvgdhwnfrclldtegkmgpnwaich

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2ajqB (B:)
sdkiihltddsfdtdvlkadgailvdfwaewcgpckmiapildeiadeyqgkltvaklni
dqnpgtapkygirgiptlllfkngevaatkvgalskgqlkefldanla

    Sequence, based on observed residues (ATOM records): (download) 
    >2ajqB (B:)
kiihltddsfdtdvlkadgailvdfwaewcgpckmiapildeiadeyqgkltvaklnidq
npgtapkygirgiptlllfkngevaatkvgalskgqlkefldanl

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >2ajqF (F:)
mivsaiaanallesvtkfhcgviydystaeyvsyrpsdfgayldaleaevargglivfhn
ghkydvpaltklaklqlnrefhlprencidtlvlsrlihsnlkdtdmgllrsgklpgkrf
gshaleawgyrlgemkgeykddfkrmleeqgeeyvdgmewwnfneemmdynvqdvvvtka
llekllsdkhyfppeidftdvgyttfwsesleavdiehraawllakqerngfpfdtkaie
elyvelaarrsellrkltetfgswyqpkggtemfchprtgkplpkypriktpkvggifkk
pknkaqregrepceldtreyvagapytpvehvvfnpssrdhiqkklqeagwvptkytdkg
apvvddevlegvrvddpekqaaidlikeylmiqkrigqsaegdkawlryvaedgkihgsv
npngavtgrathafpnlaqipgvrspygeqcraafgaehhldgitgkpwvqagidasgle
lrclahfmarfdngeyaheilngdihtknqiaaelptrdnaktfiygflygagdekigqi
vgagkergkelkkkflentpaiaalresiqqtlvessqwvageqqvkwkrrwikgldgrk
vhvrsphaalntllqsagalicklwiikteemlvekglkhgwdgdfaymawvhdeiqvgc
rteeiaqvvietaqeamrwvgdhwnfrclldtegkmgpnwaich

    Sequence, based on observed residues (ATOM records): (download) 
    >2ajqF (F:)
mivsaiaanallesvtkfhcgviydystaeyvsyrpsdfgayldaleaevargglivfhn
ghkydvpaltklaklqlnrefhlprencidtlvlsrlihsnlkdtdmgllrsgklpgkrf
gshaleawgyrlgemkgeykddfkrmleeqgeeyvdgmewwnfneemmdynvqdvvvtka
llekllsdkhyfppeidftdvgyttfwsesleavdiehraawllakqerngfpfdtkaie
elyvelaarrsellrkltetfgswyqpkggtemfchprtgkplpkypriktpkvggifkl
dtreyvagapytpvehvvfnpssrdhiqkklqeagwvptkytdkgapvvddevlegvrvd
dpekqaaidlikeylmiqkrigqsaegdkawlryvaedgkihgsvnpngavtgrathafp
nlaqipgvrspygeqcraafgaehhldgitgkpwvqagidasglelrclahfmarfdnge
yaheilngdihtknqiaaelptrdnaktfiygflygagdekigqivgagkergkelkkkf
lentpaiaalresiqqtlvessqwvageqqvkwkrrwikgldgrkvhvrsphaalntllq
sagalicklwiikteemlvekglkhgwdgdfaymawvhdeiqvgcrteeiaqvvietaqe
amrwvgdhwnfrclldtegkmgpnwaich

  • Chain 'I':
    Sequence, based on SEQRES records: (download) 
    >2ajqI (I:)
sdkiihltddsfdtdvlkadgailvdfwaewcgpckmiapildeiadeyqgkltvaklni
dqnpgtapkygirgiptlllfkngevaatkvgalskgqlkefldanla

    Sequence, based on observed residues (ATOM records): (download) 
    >2ajqI (I:)
kiihltddsfdtdvlkadgailvdfwaewcgpckmiapildeiadeyqgkltvaklnidq
npgtapkygirgiptlllfkngevaatkvgalskgqlkefldanl

  • Chain 'P':
    No sequence available.

  • Chain 'T':
    No sequence available.

  • Chain 'X':
    No sequence available.

  • Chain 'Z':
    No sequence available.