PDB entry 2ajf

View 2ajf on RCSB PDB site
Description: Structure of SARS coronavirus spike receptor-binding domain complexed with its receptor
Class: hydrolase/viral protein
Keywords: antiparallel beta sheet, extended loop, hydrolase-viral protein COMPLEX
Deposited on 2005-08-01, released 2005-09-20
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 2.9 Å
R-factor: N/A
AEROSPACI score: 0.19 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Angiotensin-converting enzyme-Related Carboxypeptidase (Ace2)
    Species: Homo sapiens [TaxId:9606]
    Gene: ACE2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2ajfa_
  • Chain 'B':
    Compound: Angiotensin-converting enzyme-Related Carboxypeptidase (Ace2)
    Species: Homo sapiens [TaxId:9606]
    Gene: ACE2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2ajfb_
  • Chain 'E':
    Compound: SARS-coronavirus spike protein
    Species: SARS coronavirus [TaxId:227859]
    Gene: S
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2ajfe1
  • Chain 'F':
    Compound: SARS-coronavirus spike protein
    Species: SARS coronavirus [TaxId:227859]
    Gene: S
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2ajff_
  • Heterogens: NAG, ZN, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >2ajfA (A:)
    stieeqaktfldkfnheaedlfyqsslaswnyntniteenvqnmnnagdkwsaflkeqst
    laqmyplqeiqnltvklqlqalqqngssvlsedkskrlntilntmstiystgkvcnpdnp
    qeclllepglneimansldynerlwaweswrsevgkqlrplyeeyvvlknemaranhyed
    ygdywrgdyevngvdgydysrgqliedvehtfeeikplyehlhayvraklmnaypsyisp
    igclpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdqawdaqrifkeaekffvsv
    glpnmtqgfwensmltdpgnvqkavchptawdlgkgdfrilmctkvtmddfltahhemgh
    iqydmayaaqpfllrnganegfheavgeimslsaatpkhlksigllspdfqedneteinf
    llkqaltivgtlpftymlekwrwmvfkgeipkdqwmkkwwemkreivgvvepvphdetyc
    dpaslfhvsndysfiryytrtlyqfqfqealcqaakhegplhkcdisnsteagqklfnml
    rlgksepwtlalenvvgaknmnvrpllnyfeplftwlkdqnknsfvgwstdwspyad
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >2ajfB (B:)
    stieeqaktfldkfnheaedlfyqsslaswnyntniteenvqnmnnagdkwsaflkeqst
    laqmyplqeiqnltvklqlqalqqngssvlsedkskrlntilntmstiystgkvcnpdnp
    qeclllepglneimansldynerlwaweswrsevgkqlrplyeeyvvlknemaranhyed
    ygdywrgdyevngvdgydysrgqliedvehtfeeikplyehlhayvraklmnaypsyisp
    igclpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdqawdaqrifkeaekffvsv
    glpnmtqgfwensmltdpgnvqkavchptawdlgkgdfrilmctkvtmddfltahhemgh
    iqydmayaaqpfllrnganegfheavgeimslsaatpkhlksigllspdfqedneteinf
    llkqaltivgtlpftymlekwrwmvfkgeipkdqwmkkwwemkreivgvvepvphdetyc
    dpaslfhvsndysfiryytrtlyqfqfqealcqaakhegplhkcdisnsteagqklfnml
    rlgksepwtlalenvvgaknmnvrpllnyfeplftwlkdqnknsfvgwstdwspyad
    

  • Chain 'E':
    Sequence, based on SEQRES records: (download)
    >2ajfE (E:)
    cpfgevfnatkfpsvyawerkkisncvadysvlynstffstfkcygvsatklndlcfsnv
    yadsfvvkgddvrqiapgqtgviadynyklpddfmgcvlawntrnidatstgnynykyry
    lrhgklrpferdisnvpfspdgkpctppalncywplndygfytttgigyqpyrvvvlsfe
    

    Sequence, based on observed residues (ATOM records): (download)
    >2ajfE (E:)
    cpfgevfnatkfpsvyawerkkisncvadysvlynstffstfkcygvsatklnvyadsfv
    vkgddvrqiapgqtgviadynyklpddfmgcvlawntrnidatstgnynykyrylrhgkl
    rpferdisnvpfspdgkpctppalncywplndygfytttgigyqpyrvvvlsfe
    

  • Chain 'F':
    Sequence, based on SEQRES records: (download)
    >2ajfF (F:)
    cpfgevfnatkfpsvyawerkkisncvadysvlynstffstfkcygvsatklndlcfsnv
    yadsfvvkgddvrqiapgqtgviadynyklpddfmgcvlawntrnidatstgnynykyry
    lrhgklrpferdisnvpfspdgkpctppalncywplndygfytttgigyqpyrvvvlsfe
    

    Sequence, based on observed residues (ATOM records): (download)
    >2ajfF (F:)
    cpfgevfnatkfpsvyawerkkisncvadysvlynstffstfkcygvsatklnvyadsfv
    vkgddvrqiapgqtgviadynyklpddfmgcvlawntrnidatstgnynykyrylrhgkl
    rpferdisnvpfspdgkpctppalncywplndygfytttgigyqpyrvvvlsfe