PDB entry 2ajc

View 2ajc on RCSB PDB site
Description: Porcine dipeptidyl peptidase IV (CD26) in complex with 4-(2-Aminoethyl)-benzene sulphonyl fluoride (AEBSF)
Class: hydrolase
Keywords: Serine protease, dipeptidyl peptidase, alpha/beta-hydrolase, beta-propeller, oxyanion hole, substrate channeling, drug design, diabetes mellitus, flexibility
Deposited on 2005-08-01, released 2006-02-28
The last revision prior to the SCOP 1.73 freeze date was dated 2006-02-28, with a file datestamp of 2007-06-28.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: 0.202
AEROSPACI score: 0.42 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: dipeptidyl peptidase 4
    Species: SUS SCROFA
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d2ajca1, d2ajca2
  • Chain 'B':
    Compound: dipeptidyl peptidase 4
    Species: SUS SCROFA
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d2ajcb1, d2ajcb2
  • Chain 'C':
    Compound: dipeptidyl peptidase 4
    Species: SUS SCROFA
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d2ajcc1, d2ajcc2
  • Chain 'D':
    Compound: dipeptidyl peptidase 4
    Species: SUS SCROFA
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d2ajcd1, d2ajcd2
  • Heterogens: NAG, SO4, 2AB, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2ajcA (A:)
srrtytltdylkstfrvkfytlqwisdheylykqennillfnaeygnssiflenstfdel
gystndysvspdrqfilfeynyvkqwrhsytasydiydlnkrqliteeripnntqwitws
pvghklayvwnndiyvknepnlssqritwtgkenviyngvtdwvyeeevfsaysalwwsp
ngtflayaqfndtevplieysfysdeslqypktvripypkagaenptvkffvvdtrtlsp
nasvtsyqivppasvligdhylcgvtwvteerislqwirraqnysiidicdydestgrwi
ssvarqhieisttgwvgrfrpaephftsdgnsfykiisneegykhichfqtdksnctfit
kgawevigiealtsdylyyisnehkgmpggrnlyriqlndytkvtclscelnpercqyys
asfsnkakyyqlrcfgpglplytlhssssdkelrvlednsaldkmlqdvqmpskkldvin
lhgtkfwyqmilpphfdkskkypllievyagpcsqkvdtvfrlswatylasteniivasf
dgrgsgyqgdkimhainrrlgtfevedqieatrqfskmgfvddkriaiwgwsyggyvtsm
vlgagsgvfkcgiavapvskweyydsvyterymglptpednldyyrnstvmsraenfkqv
eyllihgtaddnvhfqqsaqlskalvdagvdfqtmwytdedhgiasnmahqhiythmshf
lkqcfslp

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2ajcB (B:)
srrtytltdylkstfrvkfytlqwisdheylykqennillfnaeygnssiflenstfdel
gystndysvspdrqfilfeynyvkqwrhsytasydiydlnkrqliteeripnntqwitws
pvghklayvwnndiyvknepnlssqritwtgkenviyngvtdwvyeeevfsaysalwwsp
ngtflayaqfndtevplieysfysdeslqypktvripypkagaenptvkffvvdtrtlsp
nasvtsyqivppasvligdhylcgvtwvteerislqwirraqnysiidicdydestgrwi
ssvarqhieisttgwvgrfrpaephftsdgnsfykiisneegykhichfqtdksnctfit
kgawevigiealtsdylyyisnehkgmpggrnlyriqlndytkvtclscelnpercqyys
asfsnkakyyqlrcfgpglplytlhssssdkelrvlednsaldkmlqdvqmpskkldvin
lhgtkfwyqmilpphfdkskkypllievyagpcsqkvdtvfrlswatylasteniivasf
dgrgsgyqgdkimhainrrlgtfevedqieatrqfskmgfvddkriaiwgwsyggyvtsm
vlgagsgvfkcgiavapvskweyydsvyterymglptpednldyyrnstvmsraenfkqv
eyllihgtaddnvhfqqsaqlskalvdagvdfqtmwytdedhgiasnmahqhiythmshf
lkqcfslp

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2ajcC (C:)
srrtytltdylkstfrvkfytlqwisdheylykqennillfnaeygnssiflenstfdel
gystndysvspdrqfilfeynyvkqwrhsytasydiydlnkrqliteeripnntqwitws
pvghklayvwnndiyvknepnlssqritwtgkenviyngvtdwvyeeevfsaysalwwsp
ngtflayaqfndtevplieysfysdeslqypktvripypkagaenptvkffvvdtrtlsp
nasvtsyqivppasvligdhylcgvtwvteerislqwirraqnysiidicdydestgrwi
ssvarqhieisttgwvgrfrpaephftsdgnsfykiisneegykhichfqtdksnctfit
kgawevigiealtsdylyyisnehkgmpggrnlyriqlndytkvtclscelnpercqyys
asfsnkakyyqlrcfgpglplytlhssssdkelrvlednsaldkmlqdvqmpskkldvin
lhgtkfwyqmilpphfdkskkypllievyagpcsqkvdtvfrlswatylasteniivasf
dgrgsgyqgdkimhainrrlgtfevedqieatrqfskmgfvddkriaiwgwsyggyvtsm
vlgagsgvfkcgiavapvskweyydsvyterymglptpednldyyrnstvmsraenfkqv
eyllihgtaddnvhfqqsaqlskalvdagvdfqtmwytdedhgiasnmahqhiythmshf
lkqcfslp

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2ajcD (D:)
srrtytltdylkstfrvkfytlqwisdheylykqennillfnaeygnssiflenstfdel
gystndysvspdrqfilfeynyvkqwrhsytasydiydlnkrqliteeripnntqwitws
pvghklayvwnndiyvknepnlssqritwtgkenviyngvtdwvyeeevfsaysalwwsp
ngtflayaqfndtevplieysfysdeslqypktvripypkagaenptvkffvvdtrtlsp
nasvtsyqivppasvligdhylcgvtwvteerislqwirraqnysiidicdydestgrwi
ssvarqhieisttgwvgrfrpaephftsdgnsfykiisneegykhichfqtdksnctfit
kgawevigiealtsdylyyisnehkgmpggrnlyriqlndytkvtclscelnpercqyys
asfsnkakyyqlrcfgpglplytlhssssdkelrvlednsaldkmlqdvqmpskkldvin
lhgtkfwyqmilpphfdkskkypllievyagpcsqkvdtvfrlswatylasteniivasf
dgrgsgyqgdkimhainrrlgtfevedqieatrqfskmgfvddkriaiwgwsyggyvtsm
vlgagsgvfkcgiavapvskweyydsvyterymglptpednldyyrnstvmsraenfkqv
eyllihgtaddnvhfqqsaqlskalvdagvdfqtmwytdedhgiasnmahqhiythmshf
lkqcfslp