PDB entry 2ag2

View 2ag2 on RCSB PDB site
Description: Crystal Structure Analysis of GM2-activator protein complexed with Phosphatidylcholine
Class: lipid binding protein
Keywords: phospholipid-protein complex, lipid acyl chain stacking, packaging
Deposited on 2005-07-26, released 2005-10-25
The last revision prior to the SCOP 1.73 freeze date was dated 2005-10-25, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.188
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Ganglioside GM2 activator
    Species: HOMO SAPIENS
    Gene: GM2A
    Database cross-references and differences (RAF-indexed):
    • Uniprot P17900 (2-163)
      • cloning artifact (0-1)
    Domains in SCOP 1.73: d2ag2a1
  • Chain 'B':
    Compound: Ganglioside GM2 activator
    Species: HOMO SAPIENS
    Gene: GM2A
    Database cross-references and differences (RAF-indexed):
    • Uniprot P17900 (2-163)
      • cloning artifact (0-1)
    Domains in SCOP 1.73: d2ag2b1
  • Chain 'C':
    Compound: Ganglioside GM2 activator
    Species: HOMO SAPIENS
    Gene: GM2A
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d2ag2c1
  • Heterogens: CL, EPE, CH5, LP3, OLA, MYR, DAO, IPA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2ag2A (A:)
hmssfswdncdegkdpavirsltlepdpivvpgnvtlsvvgstsvplssplkvdlvleke
vaglwikipctdyigsctfehfcdvldmliptgepcpeplrtyglpchcpfkegtyslpk
sefvvpdlelpswlttgnyriesvlsssgkrlgcikiaaslkgi

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2ag2B (B:)
hmssfswdncdegkdpavirsltlepdpivvpgnvtlsvvgstsvplssplkvdlvleke
vaglwikipctdyigsctfehfcdvldmliptgepcpeplrtyglpchcpfkegtyslpk
sefvvpdlelpswlttgnyriesvlsssgkrlgcikiaaslkgi

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2ag2C (C:)
hmssfswdncdegkdpavirsltlepdpivvpgnvtlsvvgstsvplssplkvdlvleke
vaglwikipctdyigsctfehfcdvldmliptgepcpeplrtyglpchcpfkegtyslpk
sefvvpdlelpswlttgnyriesvlsssgkrlgcikiaaslkgi

    Sequence, based on observed residues (ATOM records): (download) 
    >2ag2C (C:)
ssfswdncdegkdpavirsltlepdpivvpgnvtlsvvgstsvplssplkvdlvlekeva
glwikipctdyigsctfehfcdvldmliptgepcpeplrtyglpchcpfkegtyslpkse
fvvpdlelpswlttgnyriesvlsssgkrlgcikiaaslkgi