PDB entry 2ag2

View 2ag2 on RCSB PDB site
Description: Crystal Structure Analysis of GM2-activator protein complexed with Phosphatidylcholine
Class: lipid binding protein
Keywords: phospholipid-protein complex, lipid acyl chain stacking, packaging, LIPID BINDING PROTEIN
Deposited on 2005-07-26, released 2005-10-25
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-25.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.188
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Ganglioside GM2 activator
    Species: Homo sapiens [TaxId:9606]
    Gene: GM2A
    Database cross-references and differences (RAF-indexed):
    • Uniprot P17900 (2-163)
      • cloning artifact (0-1)
    Domains in SCOPe 2.08: d2ag2a2, d2ag2a3
  • Chain 'B':
    Compound: Ganglioside GM2 activator
    Species: Homo sapiens [TaxId:9606]
    Gene: GM2A
    Database cross-references and differences (RAF-indexed):
    • Uniprot P17900 (2-163)
      • cloning artifact (0-1)
    Domains in SCOPe 2.08: d2ag2b2, d2ag2b3
  • Chain 'C':
    Compound: Ganglioside GM2 activator
    Species: Homo sapiens [TaxId:9606]
    Gene: GM2A
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2ag2c_
  • Heterogens: CL, EPE, CH5, LP3, OLA, MYR, DAO, IPA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >2ag2A (A:)
    hmssfswdncdegkdpavirsltlepdpivvpgnvtlsvvgstsvplssplkvdlvleke
    vaglwikipctdyigsctfehfcdvldmliptgepcpeplrtyglpchcpfkegtyslpk
    sefvvpdlelpswlttgnyriesvlsssgkrlgcikiaaslkgi
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >2ag2B (B:)
    hmssfswdncdegkdpavirsltlepdpivvpgnvtlsvvgstsvplssplkvdlvleke
    vaglwikipctdyigsctfehfcdvldmliptgepcpeplrtyglpchcpfkegtyslpk
    sefvvpdlelpswlttgnyriesvlsssgkrlgcikiaaslkgi
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >2ag2C (C:)
    hmssfswdncdegkdpavirsltlepdpivvpgnvtlsvvgstsvplssplkvdlvleke
    vaglwikipctdyigsctfehfcdvldmliptgepcpeplrtyglpchcpfkegtyslpk
    sefvvpdlelpswlttgnyriesvlsssgkrlgcikiaaslkgi
    

    Sequence, based on observed residues (ATOM records): (download)
    >2ag2C (C:)
    ssfswdncdegkdpavirsltlepdpivvpgnvtlsvvgstsvplssplkvdlvlekeva
    glwikipctdyigsctfehfcdvldmliptgepcpeplrtyglpchcpfkegtyslpkse
    fvvpdlelpswlttgnyriesvlsssgkrlgcikiaaslkgi