PDB entry 2afa

View 2afa on RCSB PDB site
Description: Crystal Structure of putative NAG isomerase from Salmonella typhimurium
Class: isomerase
Keywords: NAG isomerase, Dimer-of-Trimers, renin-binding protein, alpha/alpha-fold, T1489, Structural Genomics, PSI, Protein Structure Initiative, New York SGX Research Center for Structural Genomics, NYSGXRC
Deposited on 2005-07-25, released 2005-08-16
The last revision prior to the SCOPe 2.03 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.15 Å
R-factor: 0.207
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: NAG isomerase
    Species: Salmonella typhimurium [TaxId:602]
    Gene: yihS
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8ZKT7 (3-End)
      • cloning artifact (2)
      • modified residue (47)
      • modified residue (57)
      • modified residue (67)
      • modified residue (83)
      • modified residue (154)
      • modified residue (176)
      • modified residue (257)
      • modified residue (323)
      • modified residue (354)
      • cloning artifact (2)
      • modified residue (47)
      • modified residue (57)
      • modified residue (67)
      • modified residue (83)
      • modified residue (154)
      • modified residue (176)
      • modified residue (257)
      • modified residue (323)
      • modified residue (354)
    Domains in SCOPe 2.03: d2afaa1
  • Chain 'B':
    Compound: NAG isomerase
    Species: Salmonella typhimurium [TaxId:602]
    Gene: yihS
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8ZKT7 (3-End)
      • cloning artifact (2)
      • modified residue (47)
      • modified residue (57)
      • modified residue (67)
      • modified residue (83)
      • modified residue (154)
      • modified residue (176)
      • modified residue (257)
      • modified residue (323)
      • modified residue (354)
      • cloning artifact (2)
      • modified residue (47)
      • modified residue (57)
      • modified residue (67)
      • modified residue (83)
      • modified residue (154)
      • modified residue (176)
      • modified residue (257)
      • modified residue (323)
      • modified residue (354)
    Domains in SCOPe 2.03: d2afab_
  • Chain 'C':
    Compound: NAG isomerase
    Species: Salmonella typhimurium [TaxId:602]
    Gene: yihS
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8ZKT7 (3-End)
      • cloning artifact (2)
      • modified residue (47)
      • modified residue (57)
      • modified residue (67)
      • modified residue (83)
      • modified residue (154)
      • modified residue (176)
      • modified residue (257)
      • modified residue (323)
      • modified residue (354)
      • cloning artifact (2)
      • modified residue (47)
      • modified residue (57)
      • modified residue (67)
      • modified residue (83)
      • modified residue (154)
      • modified residue (176)
      • modified residue (257)
      • modified residue (323)
      • modified residue (354)
    Domains in SCOPe 2.03: d2afac_
  • Chain 'D':
    Compound: NAG isomerase
    Species: Salmonella typhimurium [TaxId:602]
    Gene: yihS
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8ZKT7 (3-End)
      • cloning artifact (2)
      • modified residue (47)
      • modified residue (57)
      • modified residue (67)
      • modified residue (83)
      • modified residue (154)
      • modified residue (176)
      • modified residue (257)
      • modified residue (323)
      • modified residue (354)
      • cloning artifact (2)
      • modified residue (47)
      • modified residue (57)
      • modified residue (67)
      • modified residue (83)
      • modified residue (154)
      • modified residue (176)
      • modified residue (257)
      • modified residue (323)
      • modified residue (354)
    Domains in SCOPe 2.03: d2afad_
  • Chain 'E':
    Compound: NAG isomerase
    Species: Salmonella typhimurium [TaxId:602]
    Gene: yihS
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8ZKT7 (3-End)
      • cloning artifact (2)
      • modified residue (47)
      • modified residue (57)
      • modified residue (67)
      • modified residue (83)
      • modified residue (154)
      • modified residue (176)
      • modified residue (257)
      • modified residue (323)
      • modified residue (354)
      • cloning artifact (2)
      • modified residue (47)
      • modified residue (57)
      • modified residue (67)
      • modified residue (83)
      • modified residue (154)
      • modified residue (176)
      • modified residue (257)
      • modified residue (323)
      • modified residue (354)
    Domains in SCOPe 2.03: d2afae_
  • Chain 'F':
    Compound: NAG isomerase
    Species: Salmonella typhimurium [TaxId:602]
    Gene: yihS
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8ZKT7 (3-End)
      • cloning artifact (2)
      • modified residue (47)
      • modified residue (57)
      • modified residue (67)
      • modified residue (83)
      • modified residue (154)
      • modified residue (176)
      • modified residue (257)
      • modified residue (323)
      • modified residue (354)
      • cloning artifact (2)
      • modified residue (47)
      • modified residue (57)
      • modified residue (67)
      • modified residue (83)
      • modified residue (154)
      • modified residue (176)
      • modified residue (257)
      • modified residue (323)
      • modified residue (354)
    Domains in SCOPe 2.03: d2afaf_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2afaA (A:)
mslkwfntlshnrwleqetdrifnfgknavvptgfgwlgnkgqikeemgthlwitarmlh
vysvaasmgrpgaydlvdhgikamngalrdkkyggwyacvndqgvvdaskqgyqhffall
gaasavttghpearklldytieviekyfwseeeqmcleswdeafsqtedyrggnanmhav
eaflivydvthdkkwldralriasviihdvarngdyrvnehfdsqwnpirdynkdnpahr
frayggtpghwiewgrlmlhlhaalearfetppawlledakglfhatirdawapdgadgf
vysvdwdgkpivrervrwpiveamgtayalytltddsqyeewyqkwwdycikylmdyeng
swwqeldadnkvttkvwdgkqdiyhllhclviprlplapglapavaaglldinakeggsh
hhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2afaA (A:)
lkwfntlshnrwleqetdrifnfgknavvptgfgwlgnkgqikeemgthlwitarmlhvy
svaasmgrpgaydlvdhgikamngalrdkkyggwyacvndqgvvdaskqgyqhffallga
asavttghpearklldytieviekyfwseeeqmcleswdeafsqtedyrggnanmhavea
flivydvthdkkwldralriasviihdvarngdyrvnehfdsqwnpirdynkdnpahrfr
ayggtpghwiewgrlmlhlhaalearfetppawlledakglfhatirdawapdgadgfvy
svdwdgkpivrervrwpiveamgtayalytltddsqyeewyqkwwdycikylmdyengsw
wqeldadnkvttgkqdiyhllhclviprlplapglapavaaglldina

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2afaB (B:)
mslkwfntlshnrwleqetdrifnfgknavvptgfgwlgnkgqikeemgthlwitarmlh
vysvaasmgrpgaydlvdhgikamngalrdkkyggwyacvndqgvvdaskqgyqhffall
gaasavttghpearklldytieviekyfwseeeqmcleswdeafsqtedyrggnanmhav
eaflivydvthdkkwldralriasviihdvarngdyrvnehfdsqwnpirdynkdnpahr
frayggtpghwiewgrlmlhlhaalearfetppawlledakglfhatirdawapdgadgf
vysvdwdgkpivrervrwpiveamgtayalytltddsqyeewyqkwwdycikylmdyeng
swwqeldadnkvttkvwdgkqdiyhllhclviprlplapglapavaaglldinakeggsh
hhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2afaB (B:)
lkwfntlshnrwleqetdrifnfgknavvptgfgwlgnkgqikeemgthlwitarmlhvy
svaasmgrpgaydlvdhgikamngalrdkkyggwyacvndqgvvdaskqgyqhffallga
asavttghpearklldytieviekyfwseeeqmcleswdeafsqtedyrggnanmhavea
flivydvthdkkwldralriasviihdvarngdyrvnehfdsqwnpirdynkdnpahrfr
ayggtpghwiewgrlmlhlhaalearfetppawlledakglfhatirdawapdgadgfvy
svdwdgkpivrervrwpiveamgtayalytltddsqyeewyqkwwdycikylmdyengsw
wqeldadnkvttgkqdiyhllhclviprlplapglapavaaglldina

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2afaC (C:)
mslkwfntlshnrwleqetdrifnfgknavvptgfgwlgnkgqikeemgthlwitarmlh
vysvaasmgrpgaydlvdhgikamngalrdkkyggwyacvndqgvvdaskqgyqhffall
gaasavttghpearklldytieviekyfwseeeqmcleswdeafsqtedyrggnanmhav
eaflivydvthdkkwldralriasviihdvarngdyrvnehfdsqwnpirdynkdnpahr
frayggtpghwiewgrlmlhlhaalearfetppawlledakglfhatirdawapdgadgf
vysvdwdgkpivrervrwpiveamgtayalytltddsqyeewyqkwwdycikylmdyeng
swwqeldadnkvttkvwdgkqdiyhllhclviprlplapglapavaaglldinakeggsh
hhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2afaC (C:)
lkwfntlshnrwleqetdrifnfgknavvptgfgwlgnkgqikeemgthlwitarmlhvy
svaasmgrpgaydlvdhgikamngalrdkkyggwyacvndqgvvdaskqgyqhffallga
asavttghpearklldytieviekyfwseeeqmcleswdeafsqtedyrggnanmhavea
flivydvthdkkwldralriasviihdvarngdyrvnehfdsqwnpirdynkdnpahrfr
ayggtpghwiewgrlmlhlhaalearfetppawlledakglfhatirdawapdgadgfvy
svdwdgkpivrervrwpiveamgtayalytltddsqyeewyqkwwdycikylmdyengsw
wqeldadnkvttgkqdiyhllhclviprlplapglapavaaglldina

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2afaD (D:)
mslkwfntlshnrwleqetdrifnfgknavvptgfgwlgnkgqikeemgthlwitarmlh
vysvaasmgrpgaydlvdhgikamngalrdkkyggwyacvndqgvvdaskqgyqhffall
gaasavttghpearklldytieviekyfwseeeqmcleswdeafsqtedyrggnanmhav
eaflivydvthdkkwldralriasviihdvarngdyrvnehfdsqwnpirdynkdnpahr
frayggtpghwiewgrlmlhlhaalearfetppawlledakglfhatirdawapdgadgf
vysvdwdgkpivrervrwpiveamgtayalytltddsqyeewyqkwwdycikylmdyeng
swwqeldadnkvttkvwdgkqdiyhllhclviprlplapglapavaaglldinakeggsh
hhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2afaD (D:)
lkwfntlshnrwleqetdrifnfgknavvptgfgwlgnkgqikeemgthlwitarmlhvy
svaasmgrpgaydlvdhgikamngalrdkkyggwyacvndqgvvdaskqgyqhffallga
asavttghpearklldytieviekyfwseeeqmcleswdeafsqtedyrggnanmhavea
flivydvthdkkwldralriasviihdvarngdyrvnehfdsqwnpirdynkdnpahrfr
ayggtpghwiewgrlmlhlhaalearfetppawlledakglfhatirdawapdgadgfvy
svdwdgkpivrervrwpiveamgtayalytltddsqyeewyqkwwdycikylmdyengsw
wqeldadnkvttgkqdiyhllhclviprlplapglapavaaglldina

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >2afaE (E:)
mslkwfntlshnrwleqetdrifnfgknavvptgfgwlgnkgqikeemgthlwitarmlh
vysvaasmgrpgaydlvdhgikamngalrdkkyggwyacvndqgvvdaskqgyqhffall
gaasavttghpearklldytieviekyfwseeeqmcleswdeafsqtedyrggnanmhav
eaflivydvthdkkwldralriasviihdvarngdyrvnehfdsqwnpirdynkdnpahr
frayggtpghwiewgrlmlhlhaalearfetppawlledakglfhatirdawapdgadgf
vysvdwdgkpivrervrwpiveamgtayalytltddsqyeewyqkwwdycikylmdyeng
swwqeldadnkvttkvwdgkqdiyhllhclviprlplapglapavaaglldinakeggsh
hhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2afaE (E:)
lkwfntlshnrwleqetdrifnfgknavvptgfgwlgnkgqikeemgthlwitarmlhvy
svaasmgrpgaydlvdhgikamngalrdkkyggwyacvndqgvvdaskqgyqhffallga
asavttghpearklldytieviekyfwseeeqmcleswdeafsqtedyrggnanmhavea
flivydvthdkkwldralriasviihdvarngdyrvnehfdsqwnpirdynkdnpahrfr
ayggtpghwiewgrlmlhlhaalearfetppawlledakglfhatirdawapdgadgfvy
svdwdgkpivrervrwpiveamgtayalytltddsqyeewyqkwwdycikylmdyengsw
wqeldadnkvttgkqdiyhllhclviprlplapglapavaaglldina

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >2afaF (F:)
mslkwfntlshnrwleqetdrifnfgknavvptgfgwlgnkgqikeemgthlwitarmlh
vysvaasmgrpgaydlvdhgikamngalrdkkyggwyacvndqgvvdaskqgyqhffall
gaasavttghpearklldytieviekyfwseeeqmcleswdeafsqtedyrggnanmhav
eaflivydvthdkkwldralriasviihdvarngdyrvnehfdsqwnpirdynkdnpahr
frayggtpghwiewgrlmlhlhaalearfetppawlledakglfhatirdawapdgadgf
vysvdwdgkpivrervrwpiveamgtayalytltddsqyeewyqkwwdycikylmdyeng
swwqeldadnkvttkvwdgkqdiyhllhclviprlplapglapavaaglldinakeggsh
hhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2afaF (F:)
lkwfntlshnrwleqetdrifnfgknavvptgfgwlgnkgqikeemgthlwitarmlhvy
svaasmgrpgaydlvdhgikamngalrdkkyggwyacvndqgvvdaskqgyqhffallga
asavttghpearklldytieviekyfwseeeqmcleswdeafsqtedyrggnanmhavea
flivydvthdkkwldralriasviihdvarngdyrvnehfdsqwnpirdynkdnpahrfr
ayggtpghwiewgrlmlhlhaalearfetppawlledakglfhatirdawapdgadgfvy
svdwdgkpivrervrwpiveamgtayalytltddsqyeewyqkwwdycikylmdyengsw
wqeldadnkvttgkqdiyhllhclviprlplapglapavaaglldina