PDB entry 2aeb

View 2aeb on RCSB PDB site
Description: Crystal structure of human arginase I at 1.29 A resolution and exploration of inhibition in immune response.
Class: hydrolase/hydrolase inhibitor
Keywords: HYDROLASE, BINUCLEAR MANGANESE CLUSTER, BORONIC ACID INHIBITOR, PERFECTLY TWINNED CRYSTAL, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on 2005-07-21, released 2005-09-06
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-03-07, with a file datestamp of 2018-03-02.
Experiment type: XRAY
Resolution: 1.29 Å
R-factor: N/A
AEROSPACI score: 0.58 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: arginase 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2aeba_
  • Chain 'B':
    Compound: arginase 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2aebb_
  • Heterogens: MN, ABH, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2aebA (A:)
msaksrtigiigapfskgqprggveegptvlrkaglleklkeqecdvkdygdlpfadipn
dspfqivknprsvgkaseqlagkvaevkkngrislvlggdhslaigsisgharvhpdlgv
iwvdahtdintpltttsgnlhgqpvsfllkelkgkipdvpgfswvtpcisakdivyiglr
dvdpgehyilktlgikyfsmtevdrlgigkvmeetlsyllgrkkrpihlsfdvdgldpsf
tpatgtpvvggltyreglyiteeiyktgllsgldimevnpslgktpeevtrtvntavait
lacfglaregnhkpidylnppk

    Sequence, based on observed residues (ATOM records): (download) 
    >2aebA (A:)
srtigiigapfskgqprggveegptvlrkaglleklkeqecdvkdygdlpfadipndspf
qivknprsvgkaseqlagkvaevkkngrislvlggdhslaigsisgharvhpdlgviwvd
ahtdintpltttsgnlhgqpvsfllkelkgkipdvpgfswvtpcisakdivyiglrdvdp
gehyilktlgikyfsmtevdrlgigkvmeetlsyllgrkkrpihlsfdvdgldpsftpat
gtpvvggltyreglyiteeiyktgllsgldimevnpslgktpeevtrtvntavaitlacf
glaregnhkpidyl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2aebB (B:)
msaksrtigiigapfskgqprggveegptvlrkaglleklkeqecdvkdygdlpfadipn
dspfqivknprsvgkaseqlagkvaevkkngrislvlggdhslaigsisgharvhpdlgv
iwvdahtdintpltttsgnlhgqpvsfllkelkgkipdvpgfswvtpcisakdivyiglr
dvdpgehyilktlgikyfsmtevdrlgigkvmeetlsyllgrkkrpihlsfdvdgldpsf
tpatgtpvvggltyreglyiteeiyktgllsgldimevnpslgktpeevtrtvntavait
lacfglaregnhkpidylnppk

    Sequence, based on observed residues (ATOM records): (download) 
    >2aebB (B:)
srtigiigapfskgqprggveegptvlrkaglleklkeqecdvkdygdlpfadipndspf
qivknprsvgkaseqlagkvaevkkngrislvlggdhslaigsisgharvhpdlgviwvd
ahtdintpltttsgnlhgqpvsfllkelkgkipdvpgfswvtpcisakdivyiglrdvdp
gehyilktlgikyfsmtevdrlgigkvmeetlsyllgrkkrpihlsfdvdgldpsftpat
gtpvvggltyreglyiteeiyktgllsgldimevnpslgktpeevtrtvntavaitlacf
glaregnhk