PDB entry 2ae8
View 2ae8 on RCSB PDB site
Description: Crystal Structure of Imidazoleglycerol-phosphate Dehydratase from Staphylococcus aureus subsp. aureus N315
Class: lyase
Keywords: beta-alpha-beta sandwich, duplication of a half-domain, imidazoleglycerol-phosphate dehydratase (IGPD), Structural Genomics, PSI, Protein Structure Initiative, Midwest Center for Structural Genomics, MCSG
Deposited on
2005-07-21, released
2005-09-06
The last revision prior to the SCOP 1.73 freeze date was dated
2005-09-06, with a file datestamp of
2007-06-04.
Experiment type: XRAY
Resolution: 2.01 Å
R-factor: 0.192
AEROSPACI score: 0.44
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Imidazoleglycerol-phosphate dehydratase
Species: Staphylococcus aureus
Database cross-references and differences (RAF-indexed):
- Uniprot P64373 (29-End)
- modified residue (29)
- modified residue (65)
- modified residue (107)
- modified residue (120)
- modified residue (124)
Domains in SCOP 1.73: d2ae8a1, d2ae8a2 - Chain 'B':
Compound: Imidazoleglycerol-phosphate dehydratase
Species: Staphylococcus aureus
Database cross-references and differences (RAF-indexed):
- Uniprot P64373 (29-End)
- cloning artifact (28)
- modified residue (29)
- modified residue (65)
- modified residue (107)
- modified residue (120)
- modified residue (124)
Domains in SCOP 1.73: d2ae8b1, d2ae8b2 - Chain 'C':
Compound: Imidazoleglycerol-phosphate dehydratase
Species: Staphylococcus aureus
Database cross-references and differences (RAF-indexed):
- Uniprot P64373 (29-End)
- modified residue (29)
- modified residue (65)
- modified residue (107)
- modified residue (120)
- modified residue (124)
Domains in SCOP 1.73: d2ae8c1, d2ae8c2 - Chain 'D':
Compound: Imidazoleglycerol-phosphate dehydratase
Species: Staphylococcus aureus
Database cross-references and differences (RAF-indexed):
- Uniprot P64373 (29-End)
- modified residue (29)
- modified residue (65)
- modified residue (107)
- modified residue (120)
- modified residue (124)
Domains in SCOP 1.73: d2ae8d1, d2ae8d2 - Chain 'E':
Compound: Imidazoleglycerol-phosphate dehydratase
Species: Staphylococcus aureus
Database cross-references and differences (RAF-indexed):
- Uniprot P64373 (29-End)
- cloning artifact (28)
- modified residue (29)
- modified residue (65)
- modified residue (107)
- modified residue (120)
- modified residue (124)
Domains in SCOP 1.73: d2ae8e1, d2ae8e2 - Chain 'F':
Compound: Imidazoleglycerol-phosphate dehydratase
Species: Staphylococcus aureus
Database cross-references and differences (RAF-indexed):
- Uniprot P64373 (29-End)
- modified residue (29)
- modified residue (65)
- modified residue (107)
- modified residue (120)
- modified residue (124)
Domains in SCOP 1.73: d2ae8f1, d2ae8f2 - Heterogens: MG, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>2ae8A (A:)
hhhhhhssgvdlgtenlyfqsnigsgsnamiyqkqrntaetqlnisisddqspshintgv
gflnhmltlftfhsglslnieaqgdidvddhhvtedigivigqlllemikdkkhfvrygt
myipmdetlarvvvdisgrpylsfnaslskekvgtfdtelveeffravvinarltthidl
irggnthheieaifkafsralgialtatddqrvpsskgvie
Sequence, based on observed residues (ATOM records): (download)
>2ae8A (A:)
miyqkqrtqlnisisddqspshintgvgflnhmltlftfhsglslnieaqgddhhvtedi
givigqlllemikdkkhfvrygtmyipmdetlarvvvdisgrpylsfnaslskekvgtfd
telveeffravvinarltthidlirggnthheieaifkafsralgialtat
- Chain 'B':
Sequence, based on SEQRES records: (download)
>2ae8B (B:)
hhhhhhssgvdlgtenlyfqsnigsgsnamiyqkqrntaetqlnisisddqspshintgv
gflnhmltlftfhsglslnieaqgdidvddhhvtedigivigqlllemikdkkhfvrygt
myipmdetlarvvvdisgrpylsfnaslskekvgtfdtelveeffravvinarltthidl
irggnthheieaifkafsralgialtatddqrvpsskgvie
Sequence, based on observed residues (ATOM records): (download)
>2ae8B (B:)
amiyqkqrnqlnisisddqspshintgvgflnhmltlftfhsglslnieaqgddhhvted
igivigqlllemikdkkhfvrygtmyipmdetlarvvvdisgrpylsfnaslskekvgtf
dtelveeffravvinarltthidlirggnthheieaifkafsralgialtat
- Chain 'C':
Sequence, based on SEQRES records: (download)
>2ae8C (C:)
hhhhhhssgvdlgtenlyfqsnigsgsnamiyqkqrntaetqlnisisddqspshintgv
gflnhmltlftfhsglslnieaqgdidvddhhvtedigivigqlllemikdkkhfvrygt
myipmdetlarvvvdisgrpylsfnaslskekvgtfdtelveeffravvinarltthidl
irggnthheieaifkafsralgialtatddqrvpsskgvie
Sequence, based on observed residues (ATOM records): (download)
>2ae8C (C:)
miyqkqrtqlnisisddqspshintgvgflnhmltlftfhsglslnieaqgddhhvtedi
givigqlllemikdkkhfvrygtmyipmdetlarvvvdisgrpylsfnaslskekvgtfd
telveeffravvinarltthidlirggnthheieaifkafsralgialtat
- Chain 'D':
Sequence, based on SEQRES records: (download)
>2ae8D (D:)
hhhhhhssgvdlgtenlyfqsnigsgsnamiyqkqrntaetqlnisisddqspshintgv
gflnhmltlftfhsglslnieaqgdidvddhhvtedigivigqlllemikdkkhfvrygt
myipmdetlarvvvdisgrpylsfnaslskekvgtfdtelveeffravvinarltthidl
irggnthheieaifkafsralgialtatddqrvpsskgvie
Sequence, based on observed residues (ATOM records): (download)
>2ae8D (D:)
miyqkqrnqlnisisddqspshintgvgflnhmltlftfhsglslnieaqgddhhvtedi
givigqlllemikdkkhfvrygtmyipmdetlarvvvdisgrpylsfnaslskekvgtfd
telveeffravvinarltthidlirggnthheieaifkafsralgialtat
- Chain 'E':
Sequence, based on SEQRES records: (download)
>2ae8E (E:)
hhhhhhssgvdlgtenlyfqsnigsgsnamiyqkqrntaetqlnisisddqspshintgv
gflnhmltlftfhsglslnieaqgdidvddhhvtedigivigqlllemikdkkhfvrygt
myipmdetlarvvvdisgrpylsfnaslskekvgtfdtelveeffravvinarltthidl
irggnthheieaifkafsralgialtatddqrvpsskgvie
Sequence, based on observed residues (ATOM records): (download)
>2ae8E (E:)
amiyqkqrnqlnisisddqspshintgvgflnhmltlftfhsglslnieaqddhhvtedi
givigqlllemikdkkhfvrygtmyipmdetlarvvvdisgrpylsfnaslskekvgtfd
telveeffravvinarltthidlirggnthheieaifkafsralgialtat
- Chain 'F':
Sequence, based on SEQRES records: (download)
>2ae8F (F:)
hhhhhhssgvdlgtenlyfqsnigsgsnamiyqkqrntaetqlnisisddqspshintgv
gflnhmltlftfhsglslnieaqgdidvddhhvtedigivigqlllemikdkkhfvrygt
myipmdetlarvvvdisgrpylsfnaslskekvgtfdtelveeffravvinarltthidl
irggnthheieaifkafsralgialtatddqrvpsskgvie
Sequence, based on observed residues (ATOM records): (download)
>2ae8F (F:)
miyqkqrtqlnisisddqspshintgvgflnhmltlftfhsglslnieaqgdhhvtedig
ivigqlllemikdkkhfvrygtmyipmdetlarvvvdisgrpylsfnaslskekvgtfdt
elveeffravvinarltthidlirggnthheieaifkafsralgialtat