PDB entry 2adu

View 2adu on RCSB PDB site
Description: Human Methionine Aminopeptidase Complex with 4-Aryl-1,2,3-triazole Inhibitor
Class: hydrolase
Keywords: hydrolase, aminopeptidase, metal binding, protease
Deposited on 2005-07-20, released 2005-09-13
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-10-11, with a file datestamp of 2017-10-06.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Methionine aminopeptidase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: METAP2, MNPEP, P67EIF2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P50579 (0-368)
      • see remark 999 (237)
    Domains in SCOPe 2.08: d2adua1, d2adua2
  • Heterogens: CO, R20, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2aduA (A:)
    kvqtdppsvpicdlypngvfpkgqeceypptqdgrtaawrttseekkaldqaseeiwndf
    reaaeahrqvrkyvmswikpgmtmieicekledcsrklikenglnaglafptgcslnnca
    ahytpnagdttvlqyddickidfgthisgriidcaftvtfnpkydtllkavkdatntgik
    cagidvrlcdvgeaiqevmesyeveidgktyqvkpirnlnghsigqyrihagktvpiikg
    geatrmeegevyaietfgstgkgvvhddmecshymknfdvghvpirlprtkhllnvinen
    fgtlafcrrwldrlgeskylmalknlcdlgivdpypplcdikgsytaqfehtillrptck
    evvsrgddy
    

    Sequence, based on observed residues (ATOM records): (download)
    >2aduA (A:)
    kvqtdppsvpicdlypngvfpkgqeceypeekkaldqaseeiwndfreaaeahrqvrkyv
    mswikpgmtmieicekledcsrklikenglnaglafptgcslnncaahytpnagdttvlq
    yddickidfgthisgriidcaftvtfnpkydtllkavkdatntgikcagidvrlcdvgea
    iqevmesyeveidgktyqvkpirnlnghsigqyrihagktvpiikggeatrmeegevyai
    etfgstgkgvvhddmecshymknfdvghvpirlprtkhllnvinenfgtlafcrrwldrl
    geskylmalknlcdlgivdpypplcdikgsytaqfehtillrptckevvsrgddy