PDB entry 2aci

View 2aci on RCSB PDB site
Description: Structure of D166A arginine deiminase
Class: hydrolase
Keywords: arginine degradation pathway, L-arginine deiminase, catalytic mechanism, HYDROLASE
Deposited on 2005-07-18, released 2005-08-09
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.198
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Arginine deiminase
    Species: Pseudomonas aeruginosa [TaxId:287]
    Gene: arcA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P13981
      • engineered (165)
    Domains in SCOPe 2.07: d2acia1
  • Chain 'B':
    Compound: Arginine deiminase
    Species: Pseudomonas aeruginosa [TaxId:287]
    Gene: arcA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P13981 (Start-417)
      • engineered (165)
    Domains in SCOPe 2.07: d2acib_
  • Chain 'C':
    Compound: Arginine deiminase
    Species: Pseudomonas aeruginosa [TaxId:287]
    Gene: arcA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P13981
      • engineered (165)
    Domains in SCOPe 2.07: d2acic_
  • Chain 'D':
    Compound: Arginine deiminase
    Species: Pseudomonas aeruginosa [TaxId:287]
    Gene: arcA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P13981 (Start-417)
      • engineered (165)
    Domains in SCOPe 2.07: d2acid_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2aciA (A:)
mstektklgvhseagklrkvmvcspglahqrltpsncdellfddviwvnqakrdhfdfvt
kmrergidvlemhnlltetiqnpealkwildrkitadsvglgltselrswlesleprkla
eyliggvaaddlpaseganilkmyreylghssfllpplpntqftrattcwiyggvtlnpm
ywparrqetllttaiykfhpefanaefeiwygdpdkdhgsstleggdvmpigngvvligm
gerssrqaigqvaqslfakgaaervivaglpksraamhldtvfsfcdrdlvtvfpevvke
ivpfslrpdpsspygmnirreektflevvaeslglkklrvvetggnsfaaereqwddgnn
vvclepgvvvgydrntytntllrkagvevitisaselgrgrggghcmtcpivrdpidy

    Sequence, based on observed residues (ATOM records): (download) 
    >2aciA (A:)
tklgvhseagklrkvmvcspglahqrltpsncdellfddviwvnqakrdhfdfvtkmrer
gidvlemhnlltetiqnpealkwildrkitadsvglgltselrswlesleprklaeylig
gvaaddlpaseganilkmyreylghssfllpplpntqftrattcwiyggvtlnpmywpar
rqetllttaiykfhpefanaefeiwygdpdkdhgsstleggdvmpigngvvligmgerss
rqaigqvaqslfakgaaervivaglpkamhldtvfsfcdrdlvtvfpevvkeivpfslrp
dpsspygmnirreektflevvaeslglkklrvvetgreqwddgnnvvclepgvvvgydrn
tytntllrkagvevitisaselgrgrggghcmtcpivrdpid

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2aciB (B:)
mstektklgvhseagklrkvmvcspglahqrltpsncdellfddviwvnqakrdhfdfvt
kmrergidvlemhnlltetiqnpealkwildrkitadsvglgltselrswlesleprkla
eyliggvaaddlpaseganilkmyreylghssfllpplpntqftrattcwiyggvtlnpm
ywparrqetllttaiykfhpefanaefeiwygdpdkdhgsstleggdvmpigngvvligm
gerssrqaigqvaqslfakgaaervivaglpksraamhldtvfsfcdrdlvtvfpevvke
ivpfslrpdpsspygmnirreektflevvaeslglkklrvvetggnsfaaereqwddgnn
vvclepgvvvgydrntytntllrkagvevitisaselgrgrggghcmtcpivrdpidy

    Sequence, based on observed residues (ATOM records): (download) 
    >2aciB (B:)
tklgvhseagklrkvmvcspglahqrltpsncdellfddviwvnqakrdhfdfvtkmrer
gidvlemhnlltetiqnpealkwildrkitadsvglgltselrswlesleprklaeylig
gvaaddlpaseganilkmyreylghssfllpplpntqftrattcwiyggvtlnpmywpar
rqetllttaiykfhpefanaefeiwygdpdkdhgsstleggdvmpigngvvligmgerss
rqaigqvaqslfakgaaervivaglpksraamhldtvfsfcdrdlvtvfpevvkeivpfs
lrpdpsspygmnirreektflevvaeslglkklrvvetgaaereqwddgnnvvclepgvv
vgydrntytntllrkagvevitisaselgrgrggghcmtcpivrdpidy

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2aciC (C:)
mstektklgvhseagklrkvmvcspglahqrltpsncdellfddviwvnqakrdhfdfvt
kmrergidvlemhnlltetiqnpealkwildrkitadsvglgltselrswlesleprkla
eyliggvaaddlpaseganilkmyreylghssfllpplpntqftrattcwiyggvtlnpm
ywparrqetllttaiykfhpefanaefeiwygdpdkdhgsstleggdvmpigngvvligm
gerssrqaigqvaqslfakgaaervivaglpksraamhldtvfsfcdrdlvtvfpevvke
ivpfslrpdpsspygmnirreektflevvaeslglkklrvvetggnsfaaereqwddgnn
vvclepgvvvgydrntytntllrkagvevitisaselgrgrggghcmtcpivrdpidy

    Sequence, based on observed residues (ATOM records): (download) 
    >2aciC (C:)
klgvhseagklrkvmvcspglahqrltpsncdellfddviwvnqakrdhfdfvtkmrerg
idvlemhnlltetiqnpealkwildrkitadsvglgltselrswlesleprklaeyligg
vaaddlpaseganilkmyreylghssfllpplpntqftrattcwiyggvtlnpmywparr
qetllttaiykfhpefanaefeiwygdpdkdhgsstleggdvmpigngvvligmgerssr
qaigqvaqslfakgaaervivaglpksamhldtvfsfcdrdlvtvfpevvkeivpfslrp
dpsspygmnirreektflevvaeslglkklrvvetgereqwddgnnvvclepgvvvgydr
ntytntllrkagvevitisaselgrgrggghcmtcpivrdpid

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2aciD (D:)
mstektklgvhseagklrkvmvcspglahqrltpsncdellfddviwvnqakrdhfdfvt
kmrergidvlemhnlltetiqnpealkwildrkitadsvglgltselrswlesleprkla
eyliggvaaddlpaseganilkmyreylghssfllpplpntqftrattcwiyggvtlnpm
ywparrqetllttaiykfhpefanaefeiwygdpdkdhgsstleggdvmpigngvvligm
gerssrqaigqvaqslfakgaaervivaglpksraamhldtvfsfcdrdlvtvfpevvke
ivpfslrpdpsspygmnirreektflevvaeslglkklrvvetggnsfaaereqwddgnn
vvclepgvvvgydrntytntllrkagvevitisaselgrgrggghcmtcpivrdpidy

    Sequence, based on observed residues (ATOM records): (download) 
    >2aciD (D:)
tklgvhseagklrkvmvcspglahqrltpsncdellfddviwvnqakrdhfdfvtkmrer
gidvlemhnlltetiqnpealkwildrkitadsvglgltselrswlesleprklaeylig
gvaaddlpaseganilkmyreylghssfllpplpntqftrattcwiyggvtlnpmywpar
rqetllttaiykfhpefanaefeiwygdpdkdhgsstleggdvmpigngvvligmgerss
rqaigqvaqslfakgaaervivaglpksraamhldtvfsfcdrdlvtvfpevvkeivpfs
lrpdpsspygmnirreektflevvaeslglkklrvvetgreqwddgnnvvclepgvvvgy
drntytntllrkagvevitisaselgrgrggghcmtcpivrdpidy