PDB entry 2abr

View 2abr on RCSB PDB site
Description: Structure of D280A arginine deiminase with L-arginine forming a S-alkylthiouronium reaction intermediate
Class: hydrolase
Keywords: arginine degradation pathway, L-arginine deiminase, X-ray structure, catalytic mechanism, HYDROLASE
Deposited on 2005-07-15, released 2005-08-09
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.9 Å
R-factor: 0.214
AEROSPACI score: 0.19 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Arginine deiminase
    Species: Pseudomonas aeruginosa [TaxId:287]
    Gene: arcA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P13981
      • engineered (279)
      • modified residue (405)
    Domains in SCOPe 2.08: d2abra1
  • Chain 'B':
    Compound: Arginine deiminase
    Species: Pseudomonas aeruginosa [TaxId:287]
    Gene: arcA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P13981
      • engineered (279)
      • modified residue (405)
    Domains in SCOPe 2.08: d2abrb_
  • Chain 'C':
    Compound: Arginine deiminase
    Species: Pseudomonas aeruginosa [TaxId:287]
    Gene: arcA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P13981
      • engineered (279)
      • modified residue (405)
    Domains in SCOPe 2.08: d2abrc_
  • Chain 'D':
    Compound: Arginine deiminase
    Species: Pseudomonas aeruginosa [TaxId:287]
    Gene: arcA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P13981
      • engineered (279)
      • modified residue (405)
    Domains in SCOPe 2.08: d2abrd_

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2abrA (A:)
mstektklgvhseagklrkvmvcspglahqrltpsncdellfddviwvnqakrdhfdfvt
kmrergidvlemhnlltetiqnpealkwildrkitadsvglgltselrswlesleprkla
eyliggvaaddlpaseganilkmyreylghssfllpplpntqftrdttcwiyggvtlnpm
ywparrqetllttaiykfhpefanaefeiwygdpdkdhgsstleggdvmpigngvvligm
gerssrqaigqvaqslfakgaaervivaglpksraamhlatvfsfcdrdlvtvfpevvke
ivpfslrpdpsspygmnirreektflevvaeslglkklrvvetggnsfaaereqwddgnn
vvclepgvvvgydrntytntllrkagvevitisaselgrgrggghcmtcpivrdpidy

    Sequence, based on observed residues (ATOM records): (download) 
    >2abrA (A:)
tklgvhseagklrkvmvcspglahqrltpsncdellfddviwvnqakrdhfdfvtkmrer
gidvlemhnlltetiqnpealkwildrkitadsvglgltselrswlesleprklaeylig
gvaaddlpaseganilkmyreylghssfllpplpntqftrdttcwiyggvtlnpmywpar
rqetllttaiykfhpefanaefeiwygdpdkdhgsstleggdvmpigngvvligmgerss
rqaigqvaqslfakgaaervivaglpksmhlatvfsfcdrdlvtvfpevvkeivpfslrp
dpsspygmnirreektflevvaeslglkklrvvetgreqwddgnnvvclepgvvvgydrn
tytntllrkagvevitisaselgrgrggghcmtcpivrdpid

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2abrB (B:)
mstektklgvhseagklrkvmvcspglahqrltpsncdellfddviwvnqakrdhfdfvt
kmrergidvlemhnlltetiqnpealkwildrkitadsvglgltselrswlesleprkla
eyliggvaaddlpaseganilkmyreylghssfllpplpntqftrdttcwiyggvtlnpm
ywparrqetllttaiykfhpefanaefeiwygdpdkdhgsstleggdvmpigngvvligm
gerssrqaigqvaqslfakgaaervivaglpksraamhlatvfsfcdrdlvtvfpevvke
ivpfslrpdpsspygmnirreektflevvaeslglkklrvvetggnsfaaereqwddgnn
vvclepgvvvgydrntytntllrkagvevitisaselgrgrggghcmtcpivrdpidy

    Sequence, based on observed residues (ATOM records): (download) 
    >2abrB (B:)
tklgvhseagklrkvmvcspglahqrltpsncdellfddviwvnqakrdhfdfvtkmrer
gidvlemhnlltetiqnpealkwildrkitadsvglgltselrswlesleprklaeylig
gvaaddlpaseganilkmyreylghssfllpplpntqftrdttcwiyggvtlnpmywpar
rqetllttaiykfhpefanaefeiwygdpdkdhgsstleggdvmpigngvvligmgerss
rqaigqvaqslfakgaaervivaglpkaamhlatvfsfcdrdlvtvfpevvkeivpfslr
pdpsspygmnirreektflevvaeslglkklrvvetgaaereqwddgnnvvclepgvvvg
ydrntytntllrkagvevitisaselgrgrggghcmtcpivrdpid

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2abrC (C:)
mstektklgvhseagklrkvmvcspglahqrltpsncdellfddviwvnqakrdhfdfvt
kmrergidvlemhnlltetiqnpealkwildrkitadsvglgltselrswlesleprkla
eyliggvaaddlpaseganilkmyreylghssfllpplpntqftrdttcwiyggvtlnpm
ywparrqetllttaiykfhpefanaefeiwygdpdkdhgsstleggdvmpigngvvligm
gerssrqaigqvaqslfakgaaervivaglpksraamhlatvfsfcdrdlvtvfpevvke
ivpfslrpdpsspygmnirreektflevvaeslglkklrvvetggnsfaaereqwddgnn
vvclepgvvvgydrntytntllrkagvevitisaselgrgrggghcmtcpivrdpidy

    Sequence, based on observed residues (ATOM records): (download) 
    >2abrC (C:)
klgvhseagklrkvmvcspglahqrltpsncdellfddviwvnqakrdhfdfvtkmrerg
idvlemhnlltetiqnpealkwildrkitadsvglgltselrswlesleprklaeyligg
vaaddlpaseganilkmyreylghssfllpplpntqftrdttcwiyggvtlnpmywparr
qetllttaiykfhpefanaefeiwygdpdkdhgsstleggdvmpigngvvligmgerssr
qaigqvaqslfakgaaervivaglpksamhlatvfsfcdrdlvtvfpevvkeivpfslrp
dpsspygmnirreektflevvaeslglkklrvvetgereqwddgnnvvclepgvvvgydr
ntytntllrkagvevitisaselgrgrggghcmtcpivrdpid

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2abrD (D:)
mstektklgvhseagklrkvmvcspglahqrltpsncdellfddviwvnqakrdhfdfvt
kmrergidvlemhnlltetiqnpealkwildrkitadsvglgltselrswlesleprkla
eyliggvaaddlpaseganilkmyreylghssfllpplpntqftrdttcwiyggvtlnpm
ywparrqetllttaiykfhpefanaefeiwygdpdkdhgsstleggdvmpigngvvligm
gerssrqaigqvaqslfakgaaervivaglpksraamhlatvfsfcdrdlvtvfpevvke
ivpfslrpdpsspygmnirreektflevvaeslglkklrvvetggnsfaaereqwddgnn
vvclepgvvvgydrntytntllrkagvevitisaselgrgrggghcmtcpivrdpidy

    Sequence, based on observed residues (ATOM records): (download) 
    >2abrD (D:)
tklgvhseagklrkvmvcspglahqrltpsncdellfddviwvnqakrdhfdfvtkmrer
gidvlemhnlltetiqnpealkwildrkitadsvglgltselrswlesleprklaeylig
gvaaddlpaseganilkmyreylghssfllpplpntqftrdttcwiyggvtlnpmywpar
rqetllttaiykfhpefanaefeiwygdpdkdhgsstleggdvmpigngvvligmgerss
rqaigqvaqslfakgaaervivaglpksrmhlatvfsfcdrdlvtvfpevvkeivpfslr
pdpsspygmnirreektflevvaeslglkklrvvetgreqwddgnnvvclepgvvvgydr
ntytntllrkagvevitisaselgrgrggghcmtcpivrdpi