PDB entry 2aa0

View 2aa0 on RCSB PDB site
Description: Crystal structure of T. gondii adenosine kinase complexed with 6-methylmercaptopurine riboside
Class: signaling protein,transferase
Keywords: ribokinase fold; alpha/beta; intermediate conformation, SIGNALING PROTEIN,TRANSFERASE
Deposited on 2005-07-13, released 2006-07-25
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.75 Å
R-factor: 0.204
AEROSPACI score: 0.51 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: adenosine kinase
    Species: Toxoplasma gondii [TaxId:5811]
    Gene: AK
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9TVW2
      • engineered (289)
      • engineered (379)
    Domains in SCOPe 2.08: d2aa0a_
  • Heterogens: CL, NA, ACT, MTP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2aa0A (A:)
mgsshhhhhhssglvprgshmavdssnsatgpmrvfaignpildlvaevpssfldefflk
rgdatlatpeqmriystldqfnptslpggsalnsvrvvqkllrkpgsagymgaigddprg
qvlkelcdkeglatrfmvapgqstgvcavlinekertlcthlgacgsfrlpedwttfasg
alifyataytltatpknalevagyahgipnaiftlnlsapfcvelykdamqslllhtnil
fgneeefahlakvhnlvaaektalstankehavevctgalrlltagqntsatklvvmtrg
hnpviaaeqtadgtvvvhevgvpvvaaekivdtngagdafvggflyalsqgktvkqcimc
gnacaqdviqhvgfslsftftsg

    Sequence, based on observed residues (ATOM records): (download) 
    >2aa0A (A:)
tgpmrvfaignpildlvaevpssfldefflkrgdatlatpeqmriystldqfnptslpgg
salnsvrvvqkllrkpgsagymgaigddprgqvlkelcdkeglatrfmvapgqstgvcav
linekertlcthlgacgsfrlpedwttfasgalifyataytltatpknalevagyahgip
naiftlnlsapfcvelykdamqslllhtnilfgneeefahlakvhnlvaaektalstank
ehavevctgalrlltagqntsatklvvmtrghnpviaaeqtadgtvvvhevgvpvvaaek
ivdtngagdafvggflyalsqgktvkqcimcgnacaqdviqhvgfslsftf