PDB entry 2a8w
View 2a8w on RCSB PDB site
Description: Crystal Structure of Human N-acetylgalactosaminyltransferase (GTA) Complexed with Beta-Methyllactoside
Class: transferase
Keywords: GTA, ABO(H), blood groups, glycosyltransferase, retaining, TRANSFERASE
Deposited on
2005-07-09, released
2005-12-13
The last revision prior to the SCOPe 2.07 freeze date was dated
2011-07-13, with a file datestamp of
2011-05-08.
Experiment type: XRAY
Resolution: 1.59 Å
R-factor: 0.21
AEROSPACI score: 0.57
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Histo-blood group ABO system transferase (NAGAT) [Includes: Glycoprotein-fucosylgalactoside alpha-N- acetylgalactosaminyltransferase (EC 2.4.1.40) (Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase) (Histo-blood group A transferase) (A transferase); Glycoprotein-fucosylgalactoside alpha- galactosyltransferase (EC 2.4.1.37) (Fucosylglycoprotein 3-alpha- galactosyltransferase) (Histo-blood group B transferase) (B transferase)] [Contains: Fucosylglycoprotein alpha-N- acetylgalactosaminyltransferase, soluble form]
Species: Homo sapiens [TaxId:9606]
Gene: ABO
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.07: d2a8wa2, d2a8wa3 - Heterogens: HG, CL, MN, UDP, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>2a8wA (A:)
fmvslprmvypqpkvltpcrkdvlvvtpwlapivwegtfnidilneqfrlqnttigltvf
aikkyvaflklfletaekhfmvghrvhyyvftdqpaavprvtlgtgrqlsvlevraykrw
qdvsmrrmemisdfcerrflsevdylvcvdvdmefrdhvgveiltplfgtlhpgfygssr
eaftyerrpqsqayipkdegdfyylggffggsvqevqrltrachqammvdqangieavwh
deshlnkyllrhkptkvlspeylwdqqllgwpavlrklrftavpknhqavrnp
Sequence, based on observed residues (ATOM records): (download)
>2a8wA (A:)
fmvslprmvypqpkvltpcrkdvlvvtpwlapivwegtfnidilneqfrlqnttigltvf
aikkyvaflklfletaekhfmvghrvhyyvftdqpaavprvtlgtgrqlsvleverrfls
evdylvcvdvdmefrdhvgveiltplfgtlhpgfygssreaftyerrpqsqayipkdegd
fyylggffggsvqevqrltrachqammvdqangieavwhdeshlnkyllrhkptkvlspe
ylwdqqllgwpavlrklrftavp