PDB entry 2a86

View 2a86 on RCSB PDB site
Description: Crystal structure of A Pantothenate synthetase complexed with AMP and beta-alanine
Class: ligase
Keywords: protein-substrate complex, Structural Genomics, PSI, Protein Structure Initiative, TB Structural Genomics Consortium, TBSGC
Deposited on 2005-07-07, released 2006-02-21
The last revision prior to the SCOP 1.73 freeze date was dated 2006-02-21, with a file datestamp of 2007-06-28.
Experiment type: XRAY
Resolution: 1.85 Å
R-factor: 0.161
AEROSPACI score: 0.51 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Pantoate--beta-alanine ligase
    Species: Mycobacterium tuberculosis
    Gene: panC
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A5R0
      • engineered (76)
    Domains in SCOP 1.73: d2a86a1
  • Chain 'B':
    Compound: Pantoate--beta-alanine ligase
    Species: Mycobacterium tuberculosis
    Gene: panC
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A5R0
      • engineered (1)
    Domains in SCOP 1.73: d2a86b1
  • Heterogens: SO4, AMP, BAL, GOL, EOH, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2a86A (A:)
maipafhpgelnvysapgdvadvsralrltgrrvmlvptmgalheghlalvraakrvpgs
vvvvsifvnpmqfgaggdldayprtpdddlaqlraegveiaftpttaamypdglrttvqp
gplaaeleggprpthfagvltvvlkllqivrpdrvffgekdyqqlvlirqlvadfnldva
vvgvptvreadglamssrnryldpaqraaavalsaaltaaahaatagaqaaldaaravld
aapgvavdylelrdiglgpmplngsgrllvaarlgttrlldniaieigtfagtdrpdgyr

    Sequence, based on observed residues (ATOM records): (download) 
    >2a86A (A:)
ipafhpgelnvysapgdvadvsralrltgrrvmlvptmgalheghlalvraakrvpgsvv
vvsifvnpmqfgaggdldayprtpdddlaqlraegveiaftpttaamypdglrttvqpgp
laaeleggprpthfagvltvvlkllqivrpdrvffgekdyqqlvlirqlvadfnldvavv
gvptvreadglamssrnryldpaqraaavalsaaltaaahaatagaqaaldaaravldaa
pgvavdylelrdiglgpmplngsgrllvaarlgttrlldniaieigtf

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2a86B (B:)
maipafhpgelnvysapgdvadvsralrltgrrvmlvptmgalheghlalvraakrvpgs
vvvvsifvnpmqfgaggdldayprtpdddlaqlraegveiaftpttaamypdglrttvqp
gplaaeleggprpthfagvltvvlkllqivrpdrvffgekdyqqlvlirqlvadfnldva
vvgvptvreadglamssrnryldpaqraaavalsaaltaaahaatagaqaaldaaravld
aapgvavdylelrdiglgpmplngsgrllvaarlgttrlldniaieigtfagtdrpdgyr

    Sequence, based on observed residues (ATOM records): (download) 
    >2a86B (B:)
aipafhpgelnvysapgdvadvsralrltgrrvmlvptmgalheghlalvraakrvpgsv
vvvsifvnpmqfrtpdddlaqlraegveiaftpttaamypdglrttvqpgplaaeleggp
rpthfagvltvvlkllqivrpdrvffgekdyqqlvlirqlvadfnldvavvgvptvread
glamssrnryldpaqraaavalsaaltaaahaatagaqaaldaaravldaapgvavdyle
lrdiglgpmplngsgrllvaarlgttrlldniaieig