PDB entry 2a7q

View 2a7q on RCSB PDB site
Description: Crystal structure of human dCK complexed with clofarabine and ADP
Class: transferase
Keywords: alpha/beta parallel beta-sheet of 5 strands, transferase
Deposited on 2005-07-05, released 2006-01-24
The last revision prior to the SCOPe 2.01 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.55 Å
R-factor: 0.213
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Deoxycytidine kinase
    Species: Homo sapiens [TaxId:9606]
    Gene: DCK
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.01: d2a7qa1
  • Heterogens: MG, ADP, CFB, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2a7qA (A:)
    gshmatppkrscpsfsassegtrikkisiegniaagkstfvnilkqlcedwevvpepvar
    wcnvqstqdefeeltmsqknggnvlqmmyekperwsftfqtyaclsriraqlaslngklk
    daekpvlffersvysdryifasnlyesecmnetewtiyqdwhdwmnnqfgqsleldgiiy
    lqatpetclhriylrgrneeqgipleyleklhykheswllhrtlktnfdylqevpiltld
    vnedfkdkyeslvekvkeflstl
    

    Sequence, based on observed residues (ATOM records): (download)
    >2a7qA (A:)
    rikkisiegniaagkstfvnilkqlcedwevvpepvarwcnvqstnggnvlqmmyekper
    wsftfqtyaclsriraqlaslngklkdaekpvlffersvysdryifasnlyesecmnete
    wtiyqdwhdwmnnqfgqsleldgiiylqatpetclhriylrgrneeqgipleyleklhyk
    heswllhrtlktnfdylqevpiltldvnedfkdkyeslvekvkeflstl