PDB entry 2a5d

View 2a5d on RCSB PDB site
Description: Structural basis for the activation of cholera toxin by human ARF6-GTP
Class: protein transport/transferase
Keywords: PROTEIN TRANSPORT/TRANSFERASE, PROTEIN TRANSPORT-TRANSFERASE complex
Deposited on 2005-06-30, released 2005-08-16
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.169
AEROSPACI score: 0.53 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: ADP-ribosylation factor 6
    Species: Homo sapiens [TaxId:9606]
    Gene: ARF6
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2a5da_
  • Chain 'B':
    Compound: Cholera enterotoxin, A chain
    Species: Vibrio cholerae [TaxId:666]
    Gene: ctxA, toxA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P01555 (1-End)
      • engineered (110)
      • engineered (112)
      • engineered (187)
    Domains in SCOPe 2.08: d2a5db1
  • Heterogens: NA, MG, GTP, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2a5dA (A:)
mgkvlskifgnkemrilmlgldaagkttilyklklgqsvttiptvgfnvetvtyknvkfn
vwdvggqdkirplwrhyytgtqglifvvdcadrdridearqelhriindremrdaiilif
ankqdlpdamkpheiqeklgltrirdrnwyvqpscatsgdglyegltwltsnyks

    Sequence, based on observed residues (ATOM records): (download) 
    >2a5dA (A:)
kemrilmlgldaagkttilyklklgqsvttiptvgfnvetvtyknvkfnvwdvggqdkir
plwrhyytgtqglifvvdcadrdridearqelhriindremrdaiilifankqdlpdamk
pheiqeklgltrirdrnwyvqpscatsgdglyegltwltsnyk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2a5dB (B:)
snddklyradsrppdeikqsgglmprgqseyfdrgtqmninlydhargtqtgfvrhddgy
vstsislrsahlvgqtilsghstyyiyviatapnmfnvndvlgaysphpddqdvsalggi
pysqiygwyrvhfgvldeqlhrnrgyrdryysnldiapaadgyglagfppehrawreepw
ihhappgsgnapr

    Sequence, based on observed residues (ATOM records): (download) 
    >2a5dB (B:)
nddklyradsrppdeikqsgglmprgqseyfdrgtqmninlydhargtqtgfvrhddgyv
stsislrsahlvgqtilsghstyyiyviatapnmfnvndvlgaysphpddqdvsalggip
ysqiygwyrvhfgvldeqlhrnrgyrdryysnldiapaadgyglagfppehrawreepwi
hhappgs