PDB entry 2a59

View 2a59 on RCSB PDB site
Description: Structure of 6,7-Dimethyl-8-ribityllumazine synthase from Schizosaccharomyces pombe mutant W27Y with bound ligand 5-nitroso-6-ribitylamino-2,4(1H,3H)-pyrimidinedione
Class: transferase
Keywords: 6, 7-Dimethyl-8-ribityllumazine synthase, Schizosaccharomyces pombe, mutant W27Y, LUSY, 5-nitroso-6-ribitylamino-2, 4(1H, 3H)-pyrimidinedione, Transferase
Deposited on 2005-06-30, released 2005-07-19
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-07-24, with a file datestamp of 2019-07-19.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: N/A
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 6,7-dimethyl-8-ribityllumazine synthase
    Species: Schizosaccharomyces pombe [TaxId:4896]
    Gene: rib4
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9UUB1
      • engineered (26)
    Domains in SCOPe 2.08: d2a59a_
  • Chain 'B':
    Compound: 6,7-dimethyl-8-ribityllumazine synthase
    Species: Schizosaccharomyces pombe [TaxId:4896]
    Gene: rib4
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9UUB1
      • engineered (26)
    Domains in SCOPe 2.08: d2a59b_
  • Chain 'C':
    Compound: 6,7-dimethyl-8-ribityllumazine synthase
    Species: Schizosaccharomyces pombe [TaxId:4896]
    Gene: rib4
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9UUB1
      • engineered (26)
    Domains in SCOPe 2.08: d2a59c_
  • Chain 'D':
    Compound: 6,7-dimethyl-8-ribityllumazine synthase
    Species: Schizosaccharomyces pombe [TaxId:4896]
    Gene: rib4
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9UUB1
      • engineered (26)
    Domains in SCOPe 2.08: d2a59d_
  • Chain 'E':
    Compound: 6,7-dimethyl-8-ribityllumazine synthase
    Species: Schizosaccharomyces pombe [TaxId:4896]
    Gene: rib4
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9UUB1
      • engineered (26)
    Domains in SCOPe 2.08: d2a59e_
  • Heterogens: PO4, LMZ, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2a59A (A:)
mfsgikgpnpsdlkgpelrilivharynlqaieplvkgavetmiekhdvklenidiesvp
gswelpqgirasiarntydavigigvlikgstmhfeyiseavvhglmrvgldsgvpvilg
lltvlneeqalyraglngghnhgndwgsaavemglkaly

    Sequence, based on observed residues (ATOM records): (download) 
    >2a59A (A:)
lkgpelrilivharynlqaieplvkgavetmiekhdvklenidiesvpgswelpqgiras
iarntydavigigvlikgstmhfeyiseavvhglmrvgldsgvpvilglltvlneeqaly
raglngghnhgndwgsaavemglkal

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2a59B (B:)
mfsgikgpnpsdlkgpelrilivharynlqaieplvkgavetmiekhdvklenidiesvp
gswelpqgirasiarntydavigigvlikgstmhfeyiseavvhglmrvgldsgvpvilg
lltvlneeqalyraglngghnhgndwgsaavemglkaly

    Sequence, based on observed residues (ATOM records): (download) 
    >2a59B (B:)
lkgpelrilivharynlqaieplvkgavetmiekhdvklenidiesvpgswelpqgiras
iarntydavigigvlikgstmhfeyiseavvhglmrvgldsgvpvilglltvlneeqaly
raglngghnhgndwgsaavemglkal

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2a59C (C:)
mfsgikgpnpsdlkgpelrilivharynlqaieplvkgavetmiekhdvklenidiesvp
gswelpqgirasiarntydavigigvlikgstmhfeyiseavvhglmrvgldsgvpvilg
lltvlneeqalyraglngghnhgndwgsaavemglkaly

    Sequence, based on observed residues (ATOM records): (download) 
    >2a59C (C:)
lkgpelrilivharynlqaieplvkgavetmiekhdvklenidiesvpgswelpqgiras
iarntydavigigvlikgstmhfeyiseavvhglmrvgldsgvpvilglltvlneeqaly
raglngghnhgndwgsaavemglkal

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2a59D (D:)
mfsgikgpnpsdlkgpelrilivharynlqaieplvkgavetmiekhdvklenidiesvp
gswelpqgirasiarntydavigigvlikgstmhfeyiseavvhglmrvgldsgvpvilg
lltvlneeqalyraglngghnhgndwgsaavemglkaly

    Sequence, based on observed residues (ATOM records): (download) 
    >2a59D (D:)
lkgpelrilivharynlqaieplvkgavetmiekhdvklenidiesvpgswelpqgiras
iarntydavigigvlikgstmhfeyiseavvhglmrvgldsgvpvilglltvlneeqaly
raglngghnhgndwgsaavemglkal

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >2a59E (E:)
mfsgikgpnpsdlkgpelrilivharynlqaieplvkgavetmiekhdvklenidiesvp
gswelpqgirasiarntydavigigvlikgstmhfeyiseavvhglmrvgldsgvpvilg
lltvlneeqalyraglngghnhgndwgsaavemglkaly

    Sequence, based on observed residues (ATOM records): (download) 
    >2a59E (E:)
lkgpelrilivharynlqaieplvkgavetmiekhdvklenidiesvpgswelpqgiras
iarntydavigigvlikgstmhfeyiseavvhglmrvgldsgvpvilglltvlneeqaly
raglngghnhgndwgsaavemglkal