PDB entry 2a57

View 2a57 on RCSB PDB site
Description: Structure of 6,7-Dimthyl-8-ribityllumazine synthase from Schizosaccharomyces pombe mutant W27Y with bound ligand 6-carboxyethyl-7-oxo-8-ribityllumazine
Class: transferase
Keywords: 6, 7-dimethyl-8-ribityllumazine synthase, riboflavin, riboflavin biosynthesis, LUSY, Transferase
Deposited on 2005-06-30, released 2005-07-19
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-07-24, with a file datestamp of 2019-07-19.
Experiment type: XRAY
Resolution: 2.75 Å
R-factor: N/A
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 6,7-dimethyl-8-ribityllumazine synthase
    Species: Schizosaccharomyces pombe [TaxId:4896]
    Gene: rib4
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9UUB1
      • engineered (26)
    Domains in SCOPe 2.08: d2a57a_
  • Chain 'B':
    Compound: 6,7-dimethyl-8-ribityllumazine synthase
    Species: Schizosaccharomyces pombe [TaxId:4896]
    Gene: rib4
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9UUB1
      • engineered (26)
    Domains in SCOPe 2.08: d2a57b_
  • Chain 'C':
    Compound: 6,7-dimethyl-8-ribityllumazine synthase
    Species: Schizosaccharomyces pombe [TaxId:4896]
    Gene: rib4
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9UUB1
      • engineered (26)
    Domains in SCOPe 2.08: d2a57c_
  • Chain 'D':
    Compound: 6,7-dimethyl-8-ribityllumazine synthase
    Species: Schizosaccharomyces pombe [TaxId:4896]
    Gene: rib4
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9UUB1
      • engineered (26)
    Domains in SCOPe 2.08: d2a57d_
  • Chain 'E':
    Compound: 6,7-dimethyl-8-ribityllumazine synthase
    Species: Schizosaccharomyces pombe [TaxId:4896]
    Gene: rib4
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9UUB1
      • engineered (26)
    Domains in SCOPe 2.08: d2a57e_
  • Heterogens: CRM, PO4

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2a57A (A:)
mfsgikgpnpsdlkgpelrilivharynlqaieplvkgavetmiekhdvklenidiesvp
gswelpqgirasiarntydavigigvlikgstmhfeyiseavvhglmrvgldsgvpvilg
lltvlneeqalyraglngghnhgndwgsaavemglkaly

    Sequence, based on observed residues (ATOM records): (download) 
    >2a57A (A:)
lkgpelrilivharynlqaieplvkgavetmiekhdvklenidiesvpgswelpqgiras
iarntydavigigvlikgstmhfeyiseavvhglmrvgldsgvpvilglltvlneeqaly
raglngghnhgndwgsaavemglkal

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2a57B (B:)
mfsgikgpnpsdlkgpelrilivharynlqaieplvkgavetmiekhdvklenidiesvp
gswelpqgirasiarntydavigigvlikgstmhfeyiseavvhglmrvgldsgvpvilg
lltvlneeqalyraglngghnhgndwgsaavemglkaly

    Sequence, based on observed residues (ATOM records): (download) 
    >2a57B (B:)
lkgpelrilivharynlqaieplvkgavetmiekhdvklenidiesvpgswelpqgiras
iarntydavigigvlikgstmhfeyiseavvhglmrvgldsgvpvilglltvlneeqaly
raglngghnhgndwgsaavemglkal

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2a57C (C:)
mfsgikgpnpsdlkgpelrilivharynlqaieplvkgavetmiekhdvklenidiesvp
gswelpqgirasiarntydavigigvlikgstmhfeyiseavvhglmrvgldsgvpvilg
lltvlneeqalyraglngghnhgndwgsaavemglkaly

    Sequence, based on observed residues (ATOM records): (download) 
    >2a57C (C:)
lkgpelrilivharynlqaieplvkgavetmiekhdvklenidiesvpgswelpqgiras
iarntydavigigvlikgstmhfeyiseavvhglmrvgldsgvpvilglltvlneeqaly
raglngghnhgndwgsaavemglkal

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2a57D (D:)
mfsgikgpnpsdlkgpelrilivharynlqaieplvkgavetmiekhdvklenidiesvp
gswelpqgirasiarntydavigigvlikgstmhfeyiseavvhglmrvgldsgvpvilg
lltvlneeqalyraglngghnhgndwgsaavemglkaly

    Sequence, based on observed residues (ATOM records): (download) 
    >2a57D (D:)
lkgpelrilivharynlqaieplvkgavetmiekhdvklenidiesvpgswelpqgiras
iarntydavigigvlikgstmhfeyiseavvhglmrvgldsgvpvilglltvlneeqaly
raglngghnhgndwgsaavemglkal

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >2a57E (E:)
mfsgikgpnpsdlkgpelrilivharynlqaieplvkgavetmiekhdvklenidiesvp
gswelpqgirasiarntydavigigvlikgstmhfeyiseavvhglmrvgldsgvpvilg
lltvlneeqalyraglngghnhgndwgsaavemglkaly

    Sequence, based on observed residues (ATOM records): (download) 
    >2a57E (E:)
lkgpelrilivharynlqaieplvkgavetmiekhdvklenidiesvpgswelpqgiras
iarntydavigigvlikgstmhfeyiseavvhglmrvgldsgvpvilglltvlneeqaly
raglngghnhgndwgsaavemglkal