PDB entry 2a40

View 2a40 on RCSB PDB site
Description: Ternary complex of the WH2 domain of WAVE with Actin-DNAse I
Class: structural protein
Keywords: WAVE, WH2, WASP, Actin, DNAse I, arp2/3
Deposited on 2005-06-27, released 2005-11-01
The last revision prior to the SCOP 1.73 freeze date was dated 2005-11-22, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.169
AEROSPACI score: 0.52 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Actin, alpha skeletal muscle
    Species: Oryctolagus cuniculus
    Database cross-references and differences (RAF-indexed):
    • Uniprot P68135
      • modified residue (72)
    Domains in SCOP 1.73: d2a40a1, d2a40a2
  • Chain 'B':
    Compound: Deoxyribonuclease-1
    Species: BOS TAURUS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d2a40b1
  • Chain 'C':
    Compound: Wiskott-Aldrich syndrome protein family member 2
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • GB AAH40943
  • Chain 'D':
    Compound: Actin, alpha skeletal muscle
    Species: Oryctolagus cuniculus
    Database cross-references and differences (RAF-indexed):
    • Uniprot P68135
      • modified residue (72)
    Domains in SCOP 1.73: d2a40d1, d2a40d2
  • Chain 'E':
    Compound: Deoxyribonuclease-1
    Species: BOS TAURUS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d2a40e1
  • Chain 'F':
    Compound: Wiskott-Aldrich syndrome protein family member 2
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • GB AAH40943
  • Heterogens: CA, MG, ATP, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2a40A (A:)
dedettalvcdngsglvkagfagddapravfpsivgrprhqgvmvgmgqkdsyvgdeaqs
krgiltlkypiehgiitnwddmekiwhhtfynelrvapeehptllteaplnpkanrekmt
qimfetfnvpamyvaiqavlslyasgrttgivldsgdgvthnvpiyegyalphaimrldl
agrdltdylmkiltergysfvttaereivrdikeklcyvaldfenemataassssleksy
elpdgqvitignerfrcpetlfqpsfigmesagihettynsimkcdidirkdlyannvms
ggttmypgiadrmqkeitalapstmkikiiapperkysvwiggsilaslstfqqmwitkq
eydeagpsivhrkcf

    Sequence, based on observed residues (ATOM records): (download) 
    >2a40A (A:)
ttalvcdngsglvkagfagddapravfpsivgrprhqgvmvgmgqkdsyvgdeaqskrgi
ltlkypiehgiitnwddmekiwhhtfynelrvapeehptllteaplnpkanrekmtqimf
etfnvpamyvaiqavlslyasgrttgivldsgdgvthnvpiyegyalphaimrldlagrd
ltdylmkiltergysfvttaereivrdikeklcyvaldfenemataassssleksyelpd
gqvitignerfrcpetlfqpsfigmesagihettynsimkcdidirkdlyannvmsggtt
mypgiadrmqkeitalapstmkikiiapperkysvwiggsilaslstfqqmwitkqeyde
ag

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2a40B (B:)
lkiaafnirtfgetkmsnatlasyivrivrrydivliqevrdshlvavgklldylnqddp
ntyhyvvseplgrnsykerylflfrpnkvsvldtyqyddgcescgndsfsrepavvkfss
hstkvkefaivalhsapsdavaeinslydvyldvqqkwhlndvmlmgdfnadcsyvtssq
wssirlrtsstfqwlipdsadttatstncaydrivvagsllqssvvpgsaapfdfqaayg
lsnemalaisdhypvevtlt

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2a40D (D:)
dedettalvcdngsglvkagfagddapravfpsivgrprhqgvmvgmgqkdsyvgdeaqs
krgiltlkypiehgiitnwddmekiwhhtfynelrvapeehptllteaplnpkanrekmt
qimfetfnvpamyvaiqavlslyasgrttgivldsgdgvthnvpiyegyalphaimrldl
agrdltdylmkiltergysfvttaereivrdikeklcyvaldfenemataassssleksy
elpdgqvitignerfrcpetlfqpsfigmesagihettynsimkcdidirkdlyannvms
ggttmypgiadrmqkeitalapstmkikiiapperkysvwiggsilaslstfqqmwitkq
eydeagpsivhrkcf

    Sequence, based on observed residues (ATOM records): (download) 
    >2a40D (D:)
ttalvcdngsglvkagfagddapravfpsivgrprhqgvmvgmgqkdsyvgdeaqskrgi
ltlkypiehgiitnwddmekiwhhtfynelrvapeehptllteaplnpkanrekmtqimf
etfnvpamyvaiqavlslyasgrttgivldsgdgvthnvpiyegyalphaimrldlagrd
ltdylmkiltergysfvttaereivrdikeklcyvaldfenemataassssleksyelpd
gqvitignerfrcpetlfqpsfigmesagihettynsimkcdidirkdlyannvmsggtt
mypgiadrmqkeitalapstmkikiiapperkysvwiggsilaslstfqqmwitkqeyde
ag

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2a40E (E:)
lkiaafnirtfgetkmsnatlasyivrivrrydivliqevrdshlvavgklldylnqddp
ntyhyvvseplgrnsykerylflfrpnkvsvldtyqyddgcescgndsfsrepavvkfss
hstkvkefaivalhsapsdavaeinslydvyldvqqkwhlndvmlmgdfnadcsyvtssq
wssirlrtsstfqwlipdsadttatstncaydrivvagsllqssvvpgsaapfdfqaayg
lsnemalaisdhypvevtlt

  • Chain 'F':
    No sequence available.