PDB entry 2a0u

View 2a0u on RCSB PDB site
Description: Crystal structure of the eukaryotic initiation factor 2B from Leishmania major at 2.1 A resolution
Class: translation
Keywords: SGPP, Structural GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, EUKARYOTIC INITIATION FACTOR, LEISHMANIA, Structural Genomics of Pathogenic Protozoa Consortium
Deposited on 2005-06-17, released 2005-08-02
The last revision prior to the SCOP 1.75 freeze date was dated 2005-08-02, with a file datestamp of 2007-06-28.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.216
AEROSPACI score: 0.5 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: initiation factor 2B
    Species: Leishmania major
    Gene: CHR36_tmp.296
    Domains in SCOP 1.75: d2a0ua1
  • Chain 'B':
    Compound: initiation factor 2B
    Species: Leishmania major
    Gene: CHR36_tmp.296
    Domains in SCOP 1.75: d2a0ub1
  • Heterogens: SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2a0uA (A:)
mahhhhhhmmskphhatlesikytpgslrlldqrklpletvfddvltvediwsaikemrv
rgapaiavsaalgiavatqrkaangelksgrevqtflltscdfvmtsrptavnlfnclrd
lkaqvdkldptkaaaevaqafvelaeavytndvafnegimrhgaahilaaakaegrdkvs
ilticntgalatsrygtalgvvrqlfydgklervyacetrpwnqgarltvyecvqedipc
tlicdgaasslmlnrkidavvvgadricqngdtankigtynlavsakfhgvklyvaaptt
tldvktasgnhveieerepteittnlvtkqrvvadgphlsiwnpvfditpselitggiit
ekgvqapaasapyydiasiiaqa

    Sequence, based on observed residues (ATOM records): (download) 
    >2a0uA (A:)
mskphhatlesikytpgslrlldqrklpletvfddvltvediwsaikemrvrgapaiavs
aalgiavatqrkaangelksgrevqtflltscdfvmtsrptavnlfnclrdlkaqvdkld
ptkaaaevaqafvelaeavytndvafnegimrhgaahilaaakaegrdkvsilticntga
latsrygtalgvvrqlfydgklervyacetrpwnqgarltvyecvqedipctlicdgaas
slmlnrkidavvvgadricqngdtankigtynlavsakfhgvklyvaaptttldvktasg
nhveieerepteittnlvtkqrvvadgphlsiwnpvfditpselitggiitekgvqapaa
sapyydiasiiaqa

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2a0uB (B:)
mahhhhhhmmskphhatlesikytpgslrlldqrklpletvfddvltvediwsaikemrv
rgapaiavsaalgiavatqrkaangelksgrevqtflltscdfvmtsrptavnlfnclrd
lkaqvdkldptkaaaevaqafvelaeavytndvafnegimrhgaahilaaakaegrdkvs
ilticntgalatsrygtalgvvrqlfydgklervyacetrpwnqgarltvyecvqedipc
tlicdgaasslmlnrkidavvvgadricqngdtankigtynlavsakfhgvklyvaaptt
tldvktasgnhveieerepteittnlvtkqrvvadgphlsiwnpvfditpselitggiit
ekgvqapaasapyydiasiiaqa

    Sequence, based on observed residues (ATOM records): (download) 
    >2a0uB (B:)
tlesikytpgslrlldqrklpletvfddvltvediwsaikemrvrgapaiavsaalgiav
atqrkaangelksgrevqtflltscdfvmtsrptavnlfnclrdlkaqvdkldptkaaae
vaqafvelaeavytndvafnegimrhgaahilaaakaegrdkvsilticntgalatsryg
talgvvrqlfydgklervyacetrpwnqgarltvyecvqedipctlicdgaasslmlnrk
idavvvgadricqngdtankigtynlavsakfhgvklyvaaptttldvktasgnhveiee
repteittnlvtkqrvvadgphlsiwnpvfditpselitggiitekgvqapaasapyydi
asiiaqa