PDB entry 22gs

View 22gs on RCSB PDB site
Description: human glutathione s-transferase p1-1 y49f mutant
Class: transferase
Keywords: transferase, glutathione, pi, detoxification, y49f
Deposited on 1998-03-10, released 1999-03-23
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-03-14, with a file datestamp of 2018-03-09.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: glutathione s-transferase p1-1
    Species: Homo sapiens [TaxId:9606]
    Gene: GSTP1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P09211 (Start-209)
      • engineered mutation (49)
    Domains in SCOPe 2.08: d22gsa1, d22gsa2
  • Chain 'B':
    Compound: glutathione s-transferase p1-1
    Species: Homo sapiens [TaxId:9606]
    Gene: GSTP1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P09211 (Start-209)
      • engineered mutation (49)
    Domains in SCOPe 2.08: d22gsb1, d22gsb2
  • Heterogens: MES, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >22gsA (A:)
mppytvvyfpvrgrcaalrmlladqgqswkeevvtvetwqegslkasclfgqlpkfqdgd
ltlyqsntilrhlgrtlglygkdqqeaalvdmvndgvedlrckyisliytnyeagkddyv
kalpgqlkpfetllsqnqggktfivgdqisfadynlldlllihevlapgcldafpllsay
vgrlsarpklkaflaspeyvnlpingngkq

    Sequence, based on observed residues (ATOM records): (download) 
    >22gsA (A:)
pytvvyfpvrgrcaalrmlladqgqswkeevvtvetwqegslkasclfgqlpkfqdgdlt
lyqsntilrhlgrtlglygkdqqeaalvdmvndgvedlrckyisliytnyeagkddyvka
lpgqlkpfetllsqnqggktfivgdqisfadynlldlllihevlapgcldafpllsayvg
rlsarpklkaflaspeyvnlpingngkq

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >22gsB (B:)
mppytvvyfpvrgrcaalrmlladqgqswkeevvtvetwqegslkasclfgqlpkfqdgd
ltlyqsntilrhlgrtlglygkdqqeaalvdmvndgvedlrckyisliytnyeagkddyv
kalpgqlkpfetllsqnqggktfivgdqisfadynlldlllihevlapgcldafpllsay
vgrlsarpklkaflaspeyvnlpingngkq

    Sequence, based on observed residues (ATOM records): (download) 
    >22gsB (B:)
pytvvyfpvrgrcaalrmlladqgqswkeevvtvetwqegslkasclfgqlpkfqdgdlt
lyqsntilrhlgrtlglygkdqqeaalvdmvndgvedlrckyisliytnyeagkddyvka
lpgqlkpfetllsqnqggktfivgdqisfadynlldlllihevlapgcldafpllsayvg
rlsarpklkaflaspeyvnlpingngkq