PDB entry 1zwh

View 1zwh on RCSB PDB site
Description: Yeast Hsp82 in complex with the novel Hsp90 inhibitor Radester amine
Class: chaperone
Keywords: HSP82, HSP90, GRP94, HtpG, Chaperone, Ligand, Radicicol, Geldanamycin
Deposited on 2005-06-03, released 2006-06-13
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-11-16, with a file datestamp of 2011-11-11.
Experiment type: XRAY
Resolution: 1.65 Å
R-factor: 0.196
AEROSPACI score: 0.56 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: ATP-dependent molecular chaperone hsp82
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: HSP82, HSP90
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1zwha2, d1zwha3
  • Heterogens: RDE, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1zwhA (A:)
mgsshhhhhhssglvprgshmasetfefqaeitqlmsliintvysnkeiflrelisnasd
aldkirykslsdpkqletepdlfiritpkpeqkvleirdsgigmtkaelinnlgtiaksg
tkafmealsagadvsmigqfgvgfyslflvadrvqvisksnddeqyiwesnaggsftvtl
devnerigrgtilrlflkddqleyleekrikevikrhsefvaypiqlvvtkevekevpip

    Sequence, based on observed residues (ATOM records): (download) 
    >1zwhA (A:)
asetfefqaeitqlmsliintvysnkeiflrelisnasdaldkirykslsdpkqletepd
lfiritpkpeqkvleirdsgigmtkaelinnlgtiaksgtkafmealsagadvsmigqfg
vgfyslflvadrvqvisksnddeqyiwesnaggsftvtldevnerigrgtilrlflkddq
leyleekrikevikrhsefvaypiqlvvtkeve