PDB entry 1zvm

View 1zvm on RCSB PDB site
Description: Crystal structure of human CD38: cyclic-ADP-ribosyl synthetase/NAD+ glycohydrolase
Class: hydrolase
Keywords: NAD hydrolase, ADPR cyclase, dimer, HYDROLASE
Deposited on 2005-06-02, released 2006-06-06
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.228
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: ADP-ribosyl cyclase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: CD38
    Database cross-references and differences (RAF-indexed):
    • Uniprot P28907
      • engineered (55)
      • engineered (119)
      • engineered (164)
      • engineered (174)
    Domains in SCOPe 2.08: d1zvma_
  • Chain 'B':
    Compound: ADP-ribosyl cyclase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: CD38
    Database cross-references and differences (RAF-indexed):
    • Uniprot P28907
      • engineered (55)
      • engineered (119)
      • engineered (164)
      • engineered (174)
    Domains in SCOPe 2.08: d1zvmb_
  • Chain 'C':
    Compound: ADP-ribosyl cyclase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: CD38
    Database cross-references and differences (RAF-indexed):
    • Uniprot P28907
      • engineered (55)
      • engineered (119)
      • engineered (164)
      • engineered (174)
    Domains in SCOPe 2.08: d1zvmc_
  • Chain 'D':
    Compound: ADP-ribosyl cyclase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: CD38
    Database cross-references and differences (RAF-indexed):
    • Uniprot P28907
      • engineered (55)
      • engineered (119)
      • engineered (164)
      • engineered (174)
    Domains in SCOPe 2.08: d1zvmd_
  • Heterogens: SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1zvmA (A:)
rwrqqwsgpgttkrfpetvlarcvkyteihpemrhvdcqsvwdafkgafiskhpcditee
dyqplmklgtqtvpcnkillwsrikdlahqftqvqrdmftledtllgyladdltwcgefa
tskinyqscpdwrkdcsnnpvsvfwktvsrrfaeaacdvvhvmldgsrskifdkdstfgs
vevhnlqpekvqtleawvihggredsrdlcqdptikelesiiskrniqfsckniyrpdkf
lqcvknpedssctsei

    Sequence, based on observed residues (ATOM records): (download) 
    >1zvmA (A:)
wrqqwsgpgttkrfpetvlarcvkyteihpemrhvdcqsvwdafkgafiskhpcditeed
yqplmklgtqtvpcnkillwsrikdlahqftqvqrdmftledtllgyladdltwcgefat
skinyqscpdwrkdcsnnpvsvfwktvsrrfaeaacdvvhvmldgsrskifdkdstfgsv
evhnlqpekvqtleawvihggredsrdlcqdptikelesiiskrniqfsckniyrpdkfl
qcvknpedssct

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1zvmB (B:)
rwrqqwsgpgttkrfpetvlarcvkyteihpemrhvdcqsvwdafkgafiskhpcditee
dyqplmklgtqtvpcnkillwsrikdlahqftqvqrdmftledtllgyladdltwcgefa
tskinyqscpdwrkdcsnnpvsvfwktvsrrfaeaacdvvhvmldgsrskifdkdstfgs
vevhnlqpekvqtleawvihggredsrdlcqdptikelesiiskrniqfsckniyrpdkf
lqcvknpedssctsei

    Sequence, based on observed residues (ATOM records): (download) 
    >1zvmB (B:)
wrqqwsgpgttkrfpetvlarcvkyteihpemrhvdcqsvwdafkgafiskhpcditeed
yqplmklgtqtvpcnkillwsrikdlahqftqvqrdmftledtllgyladdltwcgefat
skinyqscpdwrkdcsnnpvsvfwktvsrrfaeaacdvvhvmldgsrskifdkdstfgsv
evhnlqpekvqtleawvihggredsrdlcqdptikelesiiskrniqfsckniyrpdkfl
qcvknpedssct

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1zvmC (C:)
rwrqqwsgpgttkrfpetvlarcvkyteihpemrhvdcqsvwdafkgafiskhpcditee
dyqplmklgtqtvpcnkillwsrikdlahqftqvqrdmftledtllgyladdltwcgefa
tskinyqscpdwrkdcsnnpvsvfwktvsrrfaeaacdvvhvmldgsrskifdkdstfgs
vevhnlqpekvqtleawvihggredsrdlcqdptikelesiiskrniqfsckniyrpdkf
lqcvknpedssctsei

    Sequence, based on observed residues (ATOM records): (download) 
    >1zvmC (C:)
wrqqwsgpgttkrfpetvlarcvkyteihpemrhvdcqsvwdafkgafiskhpcditeed
yqplmklgtqtvpcnkillwsrikdlahqftqvqrdmftledtllgyladdltwcgefat
skinyqscpdwrkdcsnnpvsvfwktvsrrfaeaacdvvhvmldgsrskifdkdstfgsv
evhnlqpekvqtleawvihggredsrdlcqdptikelesiiskrniqfsckniyrpdkfl
qcvknpedsscts

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1zvmD (D:)
rwrqqwsgpgttkrfpetvlarcvkyteihpemrhvdcqsvwdafkgafiskhpcditee
dyqplmklgtqtvpcnkillwsrikdlahqftqvqrdmftledtllgyladdltwcgefa
tskinyqscpdwrkdcsnnpvsvfwktvsrrfaeaacdvvhvmldgsrskifdkdstfgs
vevhnlqpekvqtleawvihggredsrdlcqdptikelesiiskrniqfsckniyrpdkf
lqcvknpedssctsei

    Sequence, based on observed residues (ATOM records): (download) 
    >1zvmD (D:)
wrqqwsgpgttkrfpetvlarcvkyteihpemrhvdcqsvwdafkgafiskhpcditeed
yqplmklgtqtvpcnkillwsrikdlahqftqvqrdmftledtllgyladdltwcgefat
skinyqscpdwrkdcsnnpvsvfwktvsrrfaeaacdvvhvmldgsrskifdkdstfgsv
evhnlqpekvqtleawvihggredsrdlcqdptikelesiiskrniqfsckniyrpdkfl
qcvknpedssct