PDB entry 1ztq

View 1ztq on RCSB PDB site
Description: Crystal structure of the catalytic domain of MMP-13 complexed with WAY-033
Class: hydrolase
Keywords: MMPs, METALLOPROTEASE, HYDROLASE, MMP-13, COLLAGENASE, ZINC CHELATOR, hydroxamate, hydrophobic S1', P1' group
Deposited on 2005-05-27, released 2006-05-30
The last revision prior to the SCOP 1.75 freeze date was dated 2006-05-30, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.236
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: collagenase 3
    Species: HOMO SAPIENS
    Gene: MMP13
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1ztqa1
  • Chain 'B':
    Compound: collagenase 3
    Species: HOMO SAPIENS
    Gene: MMP13
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1ztqb1
  • Chain 'C':
    Compound: collagenase 3
    Species: HOMO SAPIENS
    Gene: MMP13
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1ztqc1
  • Chain 'D':
    Compound: collagenase 3
    Species: HOMO SAPIENS
    Gene: MMP13
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1ztqd1
  • Heterogens: ZN, CA, 033, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1ztqA (A:)
ynvfprtlkwskmnltyrivnytpdmthsevekafkkafkvwsdvtplnftrlhdgiadi
misfgikehgdfypfdgpsgllahafppgpnyggdahfdddetwtssskgynlflvaahe
fghslgldhskdpgalmfpiytytgkshfmlpdddvqgiqslygp

    Sequence, based on observed residues (ATOM records): (download) 
    >1ztqA (A:)
ynvflkwskmnltyrivnytpdmthsevekafkkafkvwsdvtplnftrlhdgiadimis
fgikehgdfypfdgpsgllahafppgpnyggdahfdddetwtssskgynlflvaahefgh
slgldhskdpgalmfpiytytgkshfmlpdddvqgiqslygp

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1ztqB (B:)
ynvfprtlkwskmnltyrivnytpdmthsevekafkkafkvwsdvtplnftrlhdgiadi
misfgikehgdfypfdgpsgllahafppgpnyggdahfdddetwtssskgynlflvaahe
fghslgldhskdpgalmfpiytytgkshfmlpdddvqgiqslygp

    Sequence, based on observed residues (ATOM records): (download) 
    >1ztqB (B:)
ynvkwskmnltyrivnytpdmthsevekafkkafkvwsdvtplnftrlhdgiadimisfg
ikehgdfypfdgpsgllahafppgpnyggdahfdddetwtssskgynlflvaahefghsl
gldhskdpgalmfpiytytgkshfmlpdddvqgiqslygp

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1ztqC (C:)
ynvfprtlkwskmnltyrivnytpdmthsevekafkkafkvwsdvtplnftrlhdgiadi
misfgikehgdfypfdgpsgllahafppgpnyggdahfdddetwtssskgynlflvaahe
fghslgldhskdpgalmfpiytytgkshfmlpdddvqgiqslygp

    Sequence, based on observed residues (ATOM records): (download) 
    >1ztqC (C:)
ynvflkwskmnltyrivnytpdmthsevekafkkafkvwsdvtplnftrlhdgiadimis
fgikehgdfypfdgpsgllahafppgpnyggdahfdddetwtssskgynlflvaahefgh
slgldhskdpgalmfpiytpdddvqgiqslygp

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1ztqD (D:)
ynvfprtlkwskmnltyrivnytpdmthsevekafkkafkvwsdvtplnftrlhdgiadi
misfgikehgdfypfdgpsgllahafppgpnyggdahfdddetwtssskgynlflvaahe
fghslgldhskdpgalmfpiytytgkshfmlpdddvqgiqslygp

    Sequence, based on observed residues (ATOM records): (download) 
    >1ztqD (D:)
ynvflkwskmnltyrivnytpdmthsevekafkkafkvwsdvtplnftrlhdgiadimis
fgikehgdfypfdgpsgllahafppgpnyggdahfdddetwtssskgynlflvaahefgh
slgldhskdpgalmfpiytfmlpdddvqgiqslygp