PDB entry 1ztq

View 1ztq on RCSB PDB site
Description: Crystal structure of the catalytic domain of MMP-13 complexed with WAY-033
Class: hydrolase
Keywords: MMPs, METALLOPROTEASE, HYDROLASE, MMP-13, COLLAGENASE, ZINC CHELATOR, hydroxamate, hydrophobic S1', P1' group
Deposited on 2005-05-27, released 2006-05-30
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.236
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: collagenase 3
    Species: Homo sapiens [TaxId:9606]
    Gene: MMP13
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1ztqa_
  • Chain 'B':
    Compound: collagenase 3
    Species: Homo sapiens [TaxId:9606]
    Gene: MMP13
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1ztqb_
  • Chain 'C':
    Compound: collagenase 3
    Species: Homo sapiens [TaxId:9606]
    Gene: MMP13
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1ztqc_
  • Chain 'D':
    Compound: collagenase 3
    Species: Homo sapiens [TaxId:9606]
    Gene: MMP13
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1ztqd_
  • Heterogens: ZN, CA, 033, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1ztqA (A:)
    ynvfprtlkwskmnltyrivnytpdmthsevekafkkafkvwsdvtplnftrlhdgiadi
    misfgikehgdfypfdgpsgllahafppgpnyggdahfdddetwtssskgynlflvaahe
    fghslgldhskdpgalmfpiytytgkshfmlpdddvqgiqslygp
    

    Sequence, based on observed residues (ATOM records): (download)
    >1ztqA (A:)
    ynvflkwskmnltyrivnytpdmthsevekafkkafkvwsdvtplnftrlhdgiadimis
    fgikehgdfypfdgpsgllahafppgpnyggdahfdddetwtssskgynlflvaahefgh
    slgldhskdpgalmfpiytytgkshfmlpdddvqgiqslygp
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >1ztqB (B:)
    ynvfprtlkwskmnltyrivnytpdmthsevekafkkafkvwsdvtplnftrlhdgiadi
    misfgikehgdfypfdgpsgllahafppgpnyggdahfdddetwtssskgynlflvaahe
    fghslgldhskdpgalmfpiytytgkshfmlpdddvqgiqslygp
    

    Sequence, based on observed residues (ATOM records): (download)
    >1ztqB (B:)
    ynvkwskmnltyrivnytpdmthsevekafkkafkvwsdvtplnftrlhdgiadimisfg
    ikehgdfypfdgpsgllahafppgpnyggdahfdddetwtssskgynlflvaahefghsl
    gldhskdpgalmfpiytytgkshfmlpdddvqgiqslygp
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >1ztqC (C:)
    ynvfprtlkwskmnltyrivnytpdmthsevekafkkafkvwsdvtplnftrlhdgiadi
    misfgikehgdfypfdgpsgllahafppgpnyggdahfdddetwtssskgynlflvaahe
    fghslgldhskdpgalmfpiytytgkshfmlpdddvqgiqslygp
    

    Sequence, based on observed residues (ATOM records): (download)
    >1ztqC (C:)
    ynvflkwskmnltyrivnytpdmthsevekafkkafkvwsdvtplnftrlhdgiadimis
    fgikehgdfypfdgpsgllahafppgpnyggdahfdddetwtssskgynlflvaahefgh
    slgldhskdpgalmfpiytpdddvqgiqslygp
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >1ztqD (D:)
    ynvfprtlkwskmnltyrivnytpdmthsevekafkkafkvwsdvtplnftrlhdgiadi
    misfgikehgdfypfdgpsgllahafppgpnyggdahfdddetwtssskgynlflvaahe
    fghslgldhskdpgalmfpiytytgkshfmlpdddvqgiqslygp
    

    Sequence, based on observed residues (ATOM records): (download)
    >1ztqD (D:)
    ynvflkwskmnltyrivnytpdmthsevekafkkafkvwsdvtplnftrlhdgiadimis
    fgikehgdfypfdgpsgllahafppgpnyggdahfdddetwtssskgynlflvaahefgh
    slgldhskdpgalmfpiytfmlpdddvqgiqslygp