PDB entry 1zt4

View 1zt4 on RCSB PDB site
Description: The crystal structure of human CD1d with and without alpha-Galactosylceramide
Class: immune system
Keywords: human CD1d, CD1, MHC class I, empty binding groove, glycolipid, alpha-galactosylceramide, alpha-GalCer, Structural Proteomics in Europe, SPINE, Structural Genomics, IMMUNE SYSTEM
Deposited on 2005-05-26, released 2005-07-19
The last revision prior to the SCOPe 2.06 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 3 Å
R-factor: 0.234
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: T-cell surface glycoprotein CD1d
    Species: Homo sapiens [TaxId:9606]
    Gene: CD1D
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1zt4a1, d1zt4a2
  • Chain 'B':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61769 (1-99)
      • initiating methionine (0)
    Domains in SCOPe 2.06: d1zt4b2, d1zt4b3
  • Chain 'C':
    Compound: T-cell surface glycoprotein CD1d
    Species: Homo sapiens [TaxId:9606]
    Gene: CD1D
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1zt4c1, d1zt4c2
  • Chain 'D':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61769 (1-99)
      • initiating methionine (0)
    Domains in SCOPe 2.06: d1zt4d2, d1zt4d3
  • Heterogens: AGH, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1zt4A (A:)
    aevpqrlfplrclqissfansswtrtdglawlgelqthswsndsdtvrslkpwsqgtfsd
    qqwetlqhifrvyrssftrdvkefakmlrlsyplelqvsagcevhpgnasnnffhvafqg
    kdilsfqgtsweptqeaplwvnlaiqvlnqdkwtretvqwllngtcpqfvsgllesgkse
    lkkqvkpkawlsrgpspgpgrlllvchvsgfypkpvwvkwmrgeqeqqgtqpgdilpnad
    etwylratldvvageaaglscrvkhsslegqdivlywggsy
    

    Sequence, based on observed residues (ATOM records): (download)
    >1zt4A (A:)
    rlfplrclqissfansswtrtdglawlgelqthswsndsdtvrslkpwsqgtfsdqqwet
    lqhifrvyrssftrdvkefakmlrlsyplelqvsagcevhpgnasnnffhvafqgkdils
    fqgtsweptqeaplwvnlaiqvlnqdkwtretvqwllngtcpqfvsgllesgkselkkqv
    kpkawlsrgpspgpgrlllvchvsgfypkpvwvkwmrgeqeqqgtqpgdilpnadetwyl
    ratldvvageaaglscrvkhsslegqdivlyw
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1zt4B (B:)
    miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
    wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >1zt4C (C:)
    aevpqrlfplrclqissfansswtrtdglawlgelqthswsndsdtvrslkpwsqgtfsd
    qqwetlqhifrvyrssftrdvkefakmlrlsyplelqvsagcevhpgnasnnffhvafqg
    kdilsfqgtsweptqeaplwvnlaiqvlnqdkwtretvqwllngtcpqfvsgllesgkse
    lkkqvkpkawlsrgpspgpgrlllvchvsgfypkpvwvkwmrgeqeqqgtqpgdilpnad
    etwylratldvvageaaglscrvkhsslegqdivlywggsy
    

    Sequence, based on observed residues (ATOM records): (download)
    >1zt4C (C:)
    pqrlfplrclqissfansswtrtdglawlgelqthswsndsdtvrslkpwsqgtfsdqqw
    etlqhifrvyrssftrdvkefakmlrlsyplelqvsagcevhpgnasnnffhvafqgkdi
    lsfqgtsweptqeaplwvnlaiqvlnqdkwtretvqwllngtcpqfvsgllesgkselkk
    qvkpkawlsrgpspgpgrlllvchvsgfypkpvwvkwmrgeqeqqgtqpgdilpnadetw
    ylratldvvageaaglscrvkhsslegqdivlywggsy
    

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1zt4D (D:)
    miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
    wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm