PDB entry 1zsr

View 1zsr on RCSB PDB site
Description: Crystal structure of wild type HIV-1 protease (BRU isolate) with a hydroxyethylamine peptidomimetic inhibitor BOC-PHE-PSI[S-CH(OH)CH2NH]-PHE-GLU-PHE-NH2
Class: hydrolase/hydrolase inhibitor
Keywords: hiv; protease; inhibitor; peptidomimetic
Deposited on 2005-05-24, released 2006-04-25
The last revision prior to the SCOP 1.73 freeze date was dated 2006-04-25, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.06 Å
R-factor: 0.202
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: protease retropepsin
  Species: HUMAN IMMUNODEFICIENCY VIRUS TYPE 1
  Database cross-references and differences (RAF-indexed):
  • Uniprot P03367
    • modified residue (66)
  Domains in SCOP 1.73: d1zsra1
• Chain 'B':
  Compound: protease retropepsin
  Species: HUMAN IMMUNODEFICIENCY VIRUS TYPE 1
  Database cross-references and differences (RAF-indexed):
  • Uniprot P03367 (0-98)
    • modified residue (66)
  Domains in SCOP 1.73: d1zsrb1
• Chain 'I':
  Compound: boc-phe-psi[s-ch(oh)ch2nh]-phe-glu-phe-nh2
  
• Heterogens: NH2, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >1zsrA (A:)
  pqitlwqrplvtikiggqlkealldtgaddtvleemslpgrwkpkmiggiggfikvrqyd
  qilieicghkaigtvlvgptpvniigrnlltqigctlnf
  

  
  
• Chain 'B':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >1zsrB (B:)
  pqitlwqrplvtikiggqlkealldtgaddtvleemslpgrwkpkmiggiggfikvrqyd
  qilieicghkaigtvlvgptpvniigrnlltqigctlnf
  

  
  
• Chain 'I':
  No sequence available.